STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
erpAIron-sulfur cluster insertion protein ErpA; Required for insertion of 4Fe-4S clusters for at least IspG. (112 aa)    
Predicted Functional Partners:
AOT07117.1
Fe-S cluster assembly scaffold IscU; A scaffold on which IscS assembles Fe-S clusters. It is likely that Fe-S cluster coordination is flexible as the role of this complex is to build and then hand off Fe-S clusters.
  
  
 0.773
AOT07242.1
Voltage-gated chloride channel; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.762
AOT09196.1
Transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.707
nfuA
Fe-S biogenesis protein NfuA; Involved in iron-sulfur cluster biogenesis. Binds a 4Fe-4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe/S proteins. Could also act as a scaffold/chaperone for damaged Fe/S proteins.
  
 
 0.700
AOT07241.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.683
AOT07916.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.
  
 
 0.677
hscB
Cobalamin 5'-phosphate synthase; Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA; Belongs to the HscB family.
 
 
 0.660
iscS
Cysteine desulfurase IscS; Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins.
 
  
 0.659
AOT09041.1
Glutaredoxin; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the glutaredoxin family. Monothiol subfamily.
 
 0.564
djlA
Molecular chaperone DjlA; Regulatory DnaK co-chaperone. Direct interaction between DnaK and DjlA is needed for the induction of the wcaABCDE operon, involved in the synthesis of a colanic acid polysaccharide capsule, possibly through activation of the RcsB/RcsC phosphotransfer signaling pathway. The colanic acid capsule may help the bacterium survive conditions outside the host.
  
 
 0.550
Your Current Organism:
Pseudoalteromonas luteoviolacea
NCBI taxonomy Id: 43657
Other names: ATCC 33492, Alteromonas luteiviolacea, Alteromonas luteo-violaceus, Alteromonas luteoviolacea, CIP 103718, DSM 6061, JCM 21275, LMG 2871, LMG:2871, NBRC 103183, P. luteoviolacea, strain CH130
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