node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
AOT07017.1 | AOT07219.1 | S4054249_03625 | S4054249_04820 | 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase; Catalyzes the formation of 2-amino-4-hydroxy-6-hydroxymethyl-7,8-dihydropteridine diphosphate from 2-amino-4-hydroxy-6-hydroxymethyl-7,8-dihydropteridine and ATP; Derived by automated computational analysis using gene prediction method: Protein Homology. | Phosphokinase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.924 |
AOT07017.1 | AOT08774.1 | S4054249_03625 | S4054249_13330 | 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase; Catalyzes the formation of 2-amino-4-hydroxy-6-hydroxymethyl-7,8-dihydropteridine diphosphate from 2-amino-4-hydroxy-6-hydroxymethyl-7,8-dihydropteridine and ATP; Derived by automated computational analysis using gene prediction method: Protein Homology. | Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. | 0.424 |
AOT07017.1 | AOT08775.1 | S4054249_03625 | S4054249_13335 | 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase; Catalyzes the formation of 2-amino-4-hydroxy-6-hydroxymethyl-7,8-dihydropteridine diphosphate from 2-amino-4-hydroxy-6-hydroxymethyl-7,8-dihydropteridine and ATP; Derived by automated computational analysis using gene prediction method: Protein Homology. | Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. | 0.653 |
AOT07017.1 | birA | S4054249_03625 | S4054249_00615 | 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase; Catalyzes the formation of 2-amino-4-hydroxy-6-hydroxymethyl-7,8-dihydropteridine diphosphate from 2-amino-4-hydroxy-6-hydroxymethyl-7,8-dihydropteridine and ATP; Derived by automated computational analysis using gene prediction method: Protein Homology. | biotin--[acetyl-CoA-carboxylase] synthetase; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio-5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon. | 0.553 |
AOT07017.1 | folE | S4054249_03625 | S4054249_20260 | 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase; Catalyzes the formation of 2-amino-4-hydroxy-6-hydroxymethyl-7,8-dihydropteridine diphosphate from 2-amino-4-hydroxy-6-hydroxymethyl-7,8-dihydropteridine and ATP; Derived by automated computational analysis using gene prediction method: Protein Homology. | GTP cyclohydrolase I FolE; Involved in the first step of tetrahydrofolate biosynthesis; catalyzes the formation of formate and 2-amino-4-hydroxy-6-(erythro-1,2, 3-trihydroxypropyl)dihydropteridine triphosphate from GTP and water; forms a homopolymer; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.992 |
AOT07017.1 | folP | S4054249_03625 | S4054249_15455 | 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase; Catalyzes the formation of 2-amino-4-hydroxy-6-hydroxymethyl-7,8-dihydropteridine diphosphate from 2-amino-4-hydroxy-6-hydroxymethyl-7,8-dihydropteridine and ATP; Derived by automated computational analysis using gene prediction method: Protein Homology. | Dihydropteroate synthase; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives. | 0.999 |
AOT07219.1 | AOT07017.1 | S4054249_04820 | S4054249_03625 | Phosphokinase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase; Catalyzes the formation of 2-amino-4-hydroxy-6-hydroxymethyl-7,8-dihydropteridine diphosphate from 2-amino-4-hydroxy-6-hydroxymethyl-7,8-dihydropteridine and ATP; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.924 |
AOT07219.1 | AOT08774.1 | S4054249_04820 | S4054249_13330 | Phosphokinase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. | 0.424 |
AOT07219.1 | AOT08775.1 | S4054249_04820 | S4054249_13335 | Phosphokinase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. | 0.653 |
AOT07219.1 | birA | S4054249_04820 | S4054249_00615 | Phosphokinase; Derived by automated computational analysis using gene prediction method: Protein Homology. | biotin--[acetyl-CoA-carboxylase] synthetase; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio-5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon. | 0.554 |
AOT07219.1 | folE | S4054249_04820 | S4054249_20260 | Phosphokinase; Derived by automated computational analysis using gene prediction method: Protein Homology. | GTP cyclohydrolase I FolE; Involved in the first step of tetrahydrofolate biosynthesis; catalyzes the formation of formate and 2-amino-4-hydroxy-6-(erythro-1,2, 3-trihydroxypropyl)dihydropteridine triphosphate from GTP and water; forms a homopolymer; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.897 |
AOT07219.1 | folP | S4054249_04820 | S4054249_15455 | Phosphokinase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Dihydropteroate synthase; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives. | 0.994 |
AOT08558.1 | AOT08775.1 | S4054249_12170 | S4054249_13335 | PTS sugar transporter; Derived by automated computational analysis using gene prediction method: Protein Homology. | Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. | 0.675 |
AOT08558.1 | folE | S4054249_12170 | S4054249_20260 | PTS sugar transporter; Derived by automated computational analysis using gene prediction method: Protein Homology. | GTP cyclohydrolase I FolE; Involved in the first step of tetrahydrofolate biosynthesis; catalyzes the formation of formate and 2-amino-4-hydroxy-6-(erythro-1,2, 3-trihydroxypropyl)dihydropteridine triphosphate from GTP and water; forms a homopolymer; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.689 |
AOT08774.1 | AOT07017.1 | S4054249_13330 | S4054249_03625 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. | 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase; Catalyzes the formation of 2-amino-4-hydroxy-6-hydroxymethyl-7,8-dihydropteridine diphosphate from 2-amino-4-hydroxy-6-hydroxymethyl-7,8-dihydropteridine and ATP; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.424 |
AOT08774.1 | AOT07219.1 | S4054249_13330 | S4054249_04820 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. | Phosphokinase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.424 |
AOT08774.1 | AOT08775.1 | S4054249_13330 | S4054249_13335 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. | Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. | 0.854 |
AOT08774.1 | AOT08776.1 | S4054249_13330 | S4054249_13340 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. | Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. | 0.790 |
AOT08774.1 | AOT08777.1 | S4054249_13330 | S4054249_13345 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. | Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. | 0.761 |
AOT08774.1 | AOT08778.1 | S4054249_13330 | S4054249_13350 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. | Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. | 0.757 |