| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ALU41977.1 | ALU42455.1 | AT705_02930 | AT705_05520 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | 23S rRNA pseudouridylate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.612 |
| ALU42454.1 | ALU42455.1 | AT705_05515 | AT705_05520 | HAD family hydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 23S rRNA pseudouridylate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.874 |
| ALU42455.1 | ALU41977.1 | AT705_05520 | AT705_02930 | 23S rRNA pseudouridylate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.612 |
| ALU42455.1 | ALU42454.1 | AT705_05520 | AT705_05515 | 23S rRNA pseudouridylate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. | HAD family hydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.874 |
| ALU42455.1 | obgE | AT705_05520 | AT705_09590 | 23S rRNA pseudouridylate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. | GTPase Obg; An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. | 0.649 |
| ALU42455.1 | rplC | AT705_05520 | AT705_12875 | 23S rRNA pseudouridylate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 50S ribosomal protein L3; One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit. | 0.635 |
| ALU42455.1 | rplD | AT705_05520 | AT705_12880 | 23S rRNA pseudouridylate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 50S ribosomal protein L4; Forms part of the polypeptide exit tunnel. | 0.600 |
| ALU42455.1 | rplU | AT705_05520 | AT705_09600 | 23S rRNA pseudouridylate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 50S ribosomal protein L21; This protein binds to 23S rRNA in the presence of protein L20; Belongs to the bacterial ribosomal protein bL21 family. | 0.616 |
| ALU42455.1 | rplX | AT705_05520 | AT705_11055 | 23S rRNA pseudouridylate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 50S ribosomal protein L24; One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit. | 0.563 |
| ALU42455.1 | rpmF | AT705_05520 | AT705_05500 | 23S rRNA pseudouridylate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Some L32 proteins have zinc finger motifs consisting of CXXC while others do not; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the bacterial ribosomal protein bL32 family. | 0.575 |
| ALU42455.1 | rsfS | AT705_05520 | AT705_06875 | 23S rRNA pseudouridylate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Ribosome silencing factor; Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation. | 0.540 |
| ALU42455.1 | trmE | AT705_05520 | AT705_12125 | 23S rRNA pseudouridylate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. | tRNA modification GTPase TrmE; In Escherichia coli this protein is involved in the biosynthesis of the hypermodified nucleoside 5-methylaminomethyl-2-thiouridine, which is found in the wobble position of some tRNAs and affects ribosomal frameshifting; shows potassium-dependent dimerization and GTP hydrolysis; also involved in regulation of glutamate-dependent acid resistance and activation of gadE; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.535 |
| obgE | ALU42455.1 | AT705_09590 | AT705_05520 | GTPase Obg; An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. | 23S rRNA pseudouridylate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.649 |
| obgE | rplC | AT705_09590 | AT705_12875 | GTPase Obg; An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. | 50S ribosomal protein L3; One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit. | 0.870 |
| obgE | rplD | AT705_09590 | AT705_12880 | GTPase Obg; An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. | 50S ribosomal protein L4; Forms part of the polypeptide exit tunnel. | 0.870 |
| obgE | rplU | AT705_09590 | AT705_09600 | GTPase Obg; An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. | 50S ribosomal protein L21; This protein binds to 23S rRNA in the presence of protein L20; Belongs to the bacterial ribosomal protein bL21 family. | 0.983 |
| obgE | rplX | AT705_09590 | AT705_11055 | GTPase Obg; An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. | 50S ribosomal protein L24; One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit. | 0.892 |
| obgE | rpmF | AT705_09590 | AT705_05500 | GTPase Obg; An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. | Some L32 proteins have zinc finger motifs consisting of CXXC while others do not; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the bacterial ribosomal protein bL32 family. | 0.883 |
| obgE | rsfS | AT705_09590 | AT705_06875 | GTPase Obg; An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. | Ribosome silencing factor; Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation. | 0.897 |
| obgE | trmE | AT705_09590 | AT705_12125 | GTPase Obg; An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. | tRNA modification GTPase TrmE; In Escherichia coli this protein is involved in the biosynthesis of the hypermodified nucleoside 5-methylaminomethyl-2-thiouridine, which is found in the wobble position of some tRNAs and affects ribosomal frameshifting; shows potassium-dependent dimerization and GTP hydrolysis; also involved in regulation of glutamate-dependent acid resistance and activation of gadE; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.610 |
