Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
gcvTGlycine cleavage system protein T; Catalyzes the transfer of a methylene carbon from the methylamine-loaded GcvH protein to tetrahydrofolate, causing the release of ammonia and the generation of reduced GcvH protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (360 aa)    
Predicted Functional Partners:
gcvH
Glycine cleavage system protein H; Part of multienzyme complex composed of H, L, P, and T proteins which catalyzes oxidation of glycine to yield carbon dioxide, ammonia, 5,10-CH2-H4folate and a reduced pyridine nucleotide; protein H is involved in transfer of methylamine group from the P to T protein; covalently bound to a lipoyl cofactor; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 0.999
ALU44565.1
Glycine dehydrogenase (aminomethyl-transferring); Acts in conjunction with GvcH to form H-protein-S-aminomethyldihydrolipoyllysine from glycine; Derived by automated computational analysis using gene prediction method: Protein Homology.
 0.999
glyA
Serine hydroxymethyltransferase; Catalyzes the reaction of glycine with 5,10-methylenetetrahydrofolate to form L-serine and tetrahydrofolate; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 0.996
ALU44428.1
Bifunctional methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase FolD; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.946
lpdA
E3 component of pyruvate and 2-oxoglutarate dehydrogenase complex; catalyzes the oxidation of dihydrolipoamide to lipoamide; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 0.945
ALU45749.1
Catalyzes the oxidation of dihydrolipoamide to lipoamide; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 0.942
purH
Phosphoribosylaminoimidazolecarboxamide formyltransferase / IMP cyclohydrolase; Involved in de novo purine biosynthesis; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
 
 0.931
metH
One of two methionine synthases in Escherichia coli; MetH catalyzes a methyl transfer reaction from methyltetrahydrofolate to homocysteine to create methionine; requires zinc for activity; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.928
purU
Formyltetrahydrofolate deformylase; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
 0.912
purN
Phosphoribosylglycinamide formyltransferase; Glycinamide ribonucleotide transformylase; GAR Tfase; catalyzes the synthesis of 5'-phosphoribosylformylglycinamide from 5'-phosphoribosylglycinamide and 10-formyltetrahydrofolate; PurN requires formyl folate for the reaction unlike PurT which uses formate; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
 
 0.911
Your Current Organism:
Pseudoalteromonas rubra
NCBI taxonomy Id: 43658
Other names: ATCC 29570, Alteromonas rubra, CIP 104110, DSM 6842, LMG 2876, LMG:2876, P. rubra
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