Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
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co-expression
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[Homology]
Score
ALU45682.1Malate synthase G; Catalyzes the formation of malate from glyoxylate and acetyl-CoA; Derived by automated computational analysis using gene prediction method: Protein Homology. (723 aa)    
Predicted Functional Partners:
ALU45681.1
Isocitrate lyase; Catalyzes the first step in the glyoxalate cycle, which converts lipids to carbohydrates; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.997
ALU42268.1
Catalyzes the synthesis of acetylphosphate or propionylphosphate from acetyl-CoA or propionyl-CoA and inorganic phosphate; when using propionyl-CoA the enzyme is functioning in the anaerobic pathway catabolizing threonine to propionate; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.975
gltA
Type II enzyme; in Escherichia coli this enzyme forms a trimer of dimers which is allosterically inhibited by NADH and competitively inhibited by alpha-ketoglutarate; allosteric inhibition is lost when Cys206 is chemically modified which also affects hexamer formation; forms oxaloacetate and acetyl-CoA and water from citrate and coenzyme A; functions in TCA cycle, glyoxylate cycle and respiration; enzyme from Helicobacter pylori is not inhibited by NADH; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
 0.946
ALU46021.1
Citrate synthase/methylcitrate synthase; Catalyzes the synthesis of 2-methylcitrate from propionyl-CoA and oxaloacetate; also catalyzes the condensation of oxaloacetate with acetyl-CoA but with a lower specificity; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
 0.946
ALU42342.1
Catalyzes the formation of fumarate from malate; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.937
acsA
Acetyl-coenzyme A synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family.
   
 0.932
ALU44290.1
Oxidizes malate to oxaloacetate; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
 0.927
prpB
2-methylisocitrate lyase; Catalyzes the formation of pyruvate and succinate from 2-methylisocitrate; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 0.921
ALU42619.1
Glyoxylate/hydroxypyruvate reductase A; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.917
ALU42225.1
acetyl-CoA acetyltransferase; Catalyzes the synthesis of acetoacetyl coenzyme A from two molecules of acetyl coenzyme A. It can also act as a thiolase, catalyzing the reverse reaction and generating two-carbon units from the four-carbon product of fatty acid oxidation; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
 
 0.914
Your Current Organism:
Pseudoalteromonas rubra
NCBI taxonomy Id: 43658
Other names: ATCC 29570, Alteromonas rubra, CIP 104110, DSM 6842, LMG 2876, LMG:2876, P. rubra
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