| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ALU42225.1 | ALU42268.1 | AT705_04285 | AT705_04510 | acetyl-CoA acetyltransferase; Catalyzes the synthesis of acetoacetyl coenzyme A from two molecules of acetyl coenzyme A. It can also act as a thiolase, catalyzing the reverse reaction and generating two-carbon units from the four-carbon product of fatty acid oxidation; Derived by automated computational analysis using gene prediction method: Protein Homology. | Catalyzes the synthesis of acetylphosphate or propionylphosphate from acetyl-CoA or propionyl-CoA and inorganic phosphate; when using propionyl-CoA the enzyme is functioning in the anaerobic pathway catabolizing threonine to propionate; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.935 |
| ALU42225.1 | ALU45681.1 | AT705_04285 | AT705_22340 | acetyl-CoA acetyltransferase; Catalyzes the synthesis of acetoacetyl coenzyme A from two molecules of acetyl coenzyme A. It can also act as a thiolase, catalyzing the reverse reaction and generating two-carbon units from the four-carbon product of fatty acid oxidation; Derived by automated computational analysis using gene prediction method: Protein Homology. | Isocitrate lyase; Catalyzes the first step in the glyoxalate cycle, which converts lipids to carbohydrates; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.812 |
| ALU42225.1 | ALU45682.1 | AT705_04285 | AT705_22345 | acetyl-CoA acetyltransferase; Catalyzes the synthesis of acetoacetyl coenzyme A from two molecules of acetyl coenzyme A. It can also act as a thiolase, catalyzing the reverse reaction and generating two-carbon units from the four-carbon product of fatty acid oxidation; Derived by automated computational analysis using gene prediction method: Protein Homology. | Malate synthase G; Catalyzes the formation of malate from glyoxylate and acetyl-CoA; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.914 |
| ALU42225.1 | ALU46021.1 | AT705_04285 | AT705_24190 | acetyl-CoA acetyltransferase; Catalyzes the synthesis of acetoacetyl coenzyme A from two molecules of acetyl coenzyme A. It can also act as a thiolase, catalyzing the reverse reaction and generating two-carbon units from the four-carbon product of fatty acid oxidation; Derived by automated computational analysis using gene prediction method: Protein Homology. | Citrate synthase/methylcitrate synthase; Catalyzes the synthesis of 2-methylcitrate from propionyl-CoA and oxaloacetate; also catalyzes the condensation of oxaloacetate with acetyl-CoA but with a lower specificity; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.933 |
| ALU42225.1 | acsA | AT705_04285 | AT705_15040 | acetyl-CoA acetyltransferase; Catalyzes the synthesis of acetoacetyl coenzyme A from two molecules of acetyl coenzyme A. It can also act as a thiolase, catalyzing the reverse reaction and generating two-carbon units from the four-carbon product of fatty acid oxidation; Derived by automated computational analysis using gene prediction method: Protein Homology. | Acetyl-coenzyme A synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. | 0.931 |
| ALU42225.1 | gltA | AT705_04285 | AT705_04195 | acetyl-CoA acetyltransferase; Catalyzes the synthesis of acetoacetyl coenzyme A from two molecules of acetyl coenzyme A. It can also act as a thiolase, catalyzing the reverse reaction and generating two-carbon units from the four-carbon product of fatty acid oxidation; Derived by automated computational analysis using gene prediction method: Protein Homology. | Type II enzyme; in Escherichia coli this enzyme forms a trimer of dimers which is allosterically inhibited by NADH and competitively inhibited by alpha-ketoglutarate; allosteric inhibition is lost when Cys206 is chemically modified which also affects hexamer formation; forms oxaloacetate and acetyl-CoA and water from citrate and coenzyme A; functions in TCA cycle, glyoxylate cycle and respiration; enzyme from Helicobacter pylori is not inhibited by NADH; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.933 |
| ALU42225.1 | prpB | AT705_04285 | AT705_24185 | acetyl-CoA acetyltransferase; Catalyzes the synthesis of acetoacetyl coenzyme A from two molecules of acetyl coenzyme A. It can also act as a thiolase, catalyzing the reverse reaction and generating two-carbon units from the four-carbon product of fatty acid oxidation; Derived by automated computational analysis using gene prediction method: Protein Homology. | 2-methylisocitrate lyase; Catalyzes the formation of pyruvate and succinate from 2-methylisocitrate; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.838 |
| ALU42268.1 | ALU42225.1 | AT705_04510 | AT705_04285 | Catalyzes the synthesis of acetylphosphate or propionylphosphate from acetyl-CoA or propionyl-CoA and inorganic phosphate; when using propionyl-CoA the enzyme is functioning in the anaerobic pathway catabolizing threonine to propionate; Derived by automated computational analysis using gene prediction method: Protein Homology. | acetyl-CoA acetyltransferase; Catalyzes the synthesis of acetoacetyl coenzyme A from two molecules of acetyl coenzyme A. It can also act as a thiolase, catalyzing the reverse reaction and generating two-carbon units from the four-carbon product of fatty acid oxidation; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.935 |
| ALU42268.1 | ALU42342.1 | AT705_04510 | AT705_04900 | Catalyzes the synthesis of acetylphosphate or propionylphosphate from acetyl-CoA or propionyl-CoA and inorganic phosphate; when using propionyl-CoA the enzyme is functioning in the anaerobic pathway catabolizing threonine to propionate; Derived by automated computational analysis using gene prediction method: Protein Homology. | Catalyzes the formation of fumarate from malate; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.795 |
| ALU42268.1 | ALU44290.1 | AT705_04510 | AT705_15805 | Catalyzes the synthesis of acetylphosphate or propionylphosphate from acetyl-CoA or propionyl-CoA and inorganic phosphate; when using propionyl-CoA the enzyme is functioning in the anaerobic pathway catabolizing threonine to propionate; Derived by automated computational analysis using gene prediction method: Protein Homology. | Oxidizes malate to oxaloacetate; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.629 |
| ALU42268.1 | ALU45681.1 | AT705_04510 | AT705_22340 | Catalyzes the synthesis of acetylphosphate or propionylphosphate from acetyl-CoA or propionyl-CoA and inorganic phosphate; when using propionyl-CoA the enzyme is functioning in the anaerobic pathway catabolizing threonine to propionate; Derived by automated computational analysis using gene prediction method: Protein Homology. | Isocitrate lyase; Catalyzes the first step in the glyoxalate cycle, which converts lipids to carbohydrates; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.973 |
| ALU42268.1 | ALU45682.1 | AT705_04510 | AT705_22345 | Catalyzes the synthesis of acetylphosphate or propionylphosphate from acetyl-CoA or propionyl-CoA and inorganic phosphate; when using propionyl-CoA the enzyme is functioning in the anaerobic pathway catabolizing threonine to propionate; Derived by automated computational analysis using gene prediction method: Protein Homology. | Malate synthase G; Catalyzes the formation of malate from glyoxylate and acetyl-CoA; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.975 |
| ALU42268.1 | ALU46021.1 | AT705_04510 | AT705_24190 | Catalyzes the synthesis of acetylphosphate or propionylphosphate from acetyl-CoA or propionyl-CoA and inorganic phosphate; when using propionyl-CoA the enzyme is functioning in the anaerobic pathway catabolizing threonine to propionate; Derived by automated computational analysis using gene prediction method: Protein Homology. | Citrate synthase/methylcitrate synthase; Catalyzes the synthesis of 2-methylcitrate from propionyl-CoA and oxaloacetate; also catalyzes the condensation of oxaloacetate with acetyl-CoA but with a lower specificity; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.948 |
| ALU42268.1 | acsA | AT705_04510 | AT705_15040 | Catalyzes the synthesis of acetylphosphate or propionylphosphate from acetyl-CoA or propionyl-CoA and inorganic phosphate; when using propionyl-CoA the enzyme is functioning in the anaerobic pathway catabolizing threonine to propionate; Derived by automated computational analysis using gene prediction method: Protein Homology. | Acetyl-coenzyme A synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. | 0.946 |
| ALU42268.1 | gltA | AT705_04510 | AT705_04195 | Catalyzes the synthesis of acetylphosphate or propionylphosphate from acetyl-CoA or propionyl-CoA and inorganic phosphate; when using propionyl-CoA the enzyme is functioning in the anaerobic pathway catabolizing threonine to propionate; Derived by automated computational analysis using gene prediction method: Protein Homology. | Type II enzyme; in Escherichia coli this enzyme forms a trimer of dimers which is allosterically inhibited by NADH and competitively inhibited by alpha-ketoglutarate; allosteric inhibition is lost when Cys206 is chemically modified which also affects hexamer formation; forms oxaloacetate and acetyl-CoA and water from citrate and coenzyme A; functions in TCA cycle, glyoxylate cycle and respiration; enzyme from Helicobacter pylori is not inhibited by NADH; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.506 |
| ALU42268.1 | prpB | AT705_04510 | AT705_24185 | Catalyzes the synthesis of acetylphosphate or propionylphosphate from acetyl-CoA or propionyl-CoA and inorganic phosphate; when using propionyl-CoA the enzyme is functioning in the anaerobic pathway catabolizing threonine to propionate; Derived by automated computational analysis using gene prediction method: Protein Homology. | 2-methylisocitrate lyase; Catalyzes the formation of pyruvate and succinate from 2-methylisocitrate; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.800 |
| ALU42342.1 | ALU42268.1 | AT705_04900 | AT705_04510 | Catalyzes the formation of fumarate from malate; Derived by automated computational analysis using gene prediction method: Protein Homology. | Catalyzes the synthesis of acetylphosphate or propionylphosphate from acetyl-CoA or propionyl-CoA and inorganic phosphate; when using propionyl-CoA the enzyme is functioning in the anaerobic pathway catabolizing threonine to propionate; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.795 |
| ALU42342.1 | ALU44290.1 | AT705_04900 | AT705_15805 | Catalyzes the formation of fumarate from malate; Derived by automated computational analysis using gene prediction method: Protein Homology. | Oxidizes malate to oxaloacetate; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.997 |
| ALU42342.1 | ALU45681.1 | AT705_04900 | AT705_22340 | Catalyzes the formation of fumarate from malate; Derived by automated computational analysis using gene prediction method: Protein Homology. | Isocitrate lyase; Catalyzes the first step in the glyoxalate cycle, which converts lipids to carbohydrates; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.589 |
| ALU42342.1 | ALU45682.1 | AT705_04900 | AT705_22345 | Catalyzes the formation of fumarate from malate; Derived by automated computational analysis using gene prediction method: Protein Homology. | Malate synthase G; Catalyzes the formation of malate from glyoxylate and acetyl-CoA; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.937 |