STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
pipB2Secreted effector protein pipB2. (206 aa)    
Predicted Functional Partners:
gyrB_2
DNA gyrase subunit B; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
    
 
 0.910
KZM33803.1
Hypothetical protein.
  
  
 0.585
gyrB_1
DNA gyrase subunit B.
    
 
 0.553
rpoE_1
ECF RNA polymerase sigma-E factor; Belongs to the sigma-70 factor family. ECF subfamily.
  
   0.513
KZM36237.1
Hypothetical protein.
       0.473
spkB
Serine/threonine-protein kinase B.
  
     0.461
KZM36928.1
Hypothetical protein.
  
 
   0.452
KZM34315.1
Hypothetical protein.
  
 
   0.438
KZM33804.1
Hypothetical protein.
  
  
 0.430
Your Current Organism:
Oerskovia enterophila
NCBI taxonomy Id: 43678
Other names: ATCC 35307, DSM 43852, HMGB B1078, IFO 14295, JCM 7350, NBRC 14295, NRRL B-16223, O. enterophila, Promicromonospora enterophila, strain DFA-19
Server load: low (20%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.