STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Kpol_1028p31PPM-type phosphatase domain-containing protein. (472 aa)    
Predicted Functional Partners:
Kpol_1032p29
N-acetyltransferase domain-containing protein.
    
   0.625
Kpol_316p4
Aldedh domain-containing protein.
   
   0.567
Kpol_1029p14
PPM-type phosphatase domain-containing protein.
    
 
 0.512
Kpol_1032p57
Formyl_trans_N domain-containing protein.
  
   0.497
Kpol_209p3
Protein phosphatase; Belongs to the PP2C family.
    
 
 0.496
Kpol_543p55
Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.
   
 0.469
Kpol_534p45
Pyruvate dehydrogenase E1 component subunit beta; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2.
    
 0.449
Kpol_388p1
Uncharacterized protein.
   
 
 0.443
Kpol_461p3
Mediator of RNA polymerase II transcription subunit 31; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
    
   0.436
Kpol_1058p10
Mediator of RNA polymerase II transcription subunit 14; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
    
   0.426
Your Current Organism:
Vanderwaltozyma polyspora
NCBI taxonomy Id: 436907
Other names: V. polyspora DSM 70294, Vanderwaltozyma polyspora DSM 70294, Vanderwaltozyma polyspora DSMZ 70294
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.