STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Kpol_1048p19Uncharacterized protein. (446 aa)    
Predicted Functional Partners:
Kpol_2000p53
AAA_16 domain-containing protein.
    
 0.999
Kpol_2002p52
Cell division control protein; Belongs to the CDC6/cdc18 family.
    
 0.999
Kpol_534p55
ORC_WH_C domain-containing protein.
    
 0.999
Kpol_1001p11
Origin recognition complex subunit 1; Component of the origin recognition complex (ORC) that binds origins of replication. DNA-binding is ATP-dependent, however specific DNA sequences that define origins of replication have not been identified so far. ORC is required to assemble the pre-replication complex necessary to initiate DNA replication.
    
 0.999
Kpol_1008p15
ORC4_C domain-containing protein.
    
 0.999
Kpol_251p3
Uncharacterized protein.
    
 0.999
Kpol_1007p8
DNA helicase; Belongs to the MCM family.
    
 0.998
Kpol_1012p2
Uncharacterized protein.
    
 0.995
Kpol_1045p78
WD_REPEATS_REGION domain-containing protein.
    
   0.957
Kpol_1058p45
Histone acetyltransferase type B catalytic subunit; Catalytic component of the histone acetylase B (HAT-B) complex. Has intrinsic substrate specificity that modifies lysine in recognition sequence GXGKXG. Involved in DNA double-strand break repair; Belongs to the HAT1 family.
    
   0.957
Your Current Organism:
Vanderwaltozyma polyspora
NCBI taxonomy Id: 436907
Other names: V. polyspora DSM 70294, Vanderwaltozyma polyspora DSM 70294, Vanderwaltozyma polyspora DSMZ 70294
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.