Genes that are sometimes fused into single open reading frames.
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Databases
Known metabolic pathways, protein complexes, signal transduction pathways, etc ... from curated databases.
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Coexpression
Proteins whose genes are observed to be correlated in expression, across a large number of experiments.
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Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes: query proteins and first shell of interactors
white nodes: second shell of interactors
Node Content
empty nodes: proteins of unknown 3D structure
filled nodes: a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Kpol_520p28
Cytochrome b5 heme-binding domain-containing protein; Belongs to the cytochrome b5 family. (218 aa)
Predicted Functional Partners:
Kpol_1035p8
Ferrochelatase; Catalyzes the ferrous insertion into protoporphyrin IX.
0.413
Your Current Organism:
Vanderwaltozyma polyspora
NCBI taxonomy Id: 436907 Other names: V. polyspora DSM 70294, Vanderwaltozyma polyspora DSM 70294, Vanderwaltozyma polyspora DSMZ 70294