STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EFG1rRNA-processing protein EFG1; Involved in rRNA processing; Belongs to the EFG1 family. (230 aa)    
Predicted Functional Partners:
NOP16
Nucleolar protein 16; Involved in the biogenesis of the 60S ribosomal subunit.
   
    0.794
RRP36
rRNA biogenesis protein RRP36; Component of the 90S pre-ribosome involved in the maturation of rRNAs. Required for early cleavages of the pre-RNAs in the 40S ribosomal subunit maturation pathway (By similarity).
   
    0.738
Kpol_1058p46
Uncharacterized protein.
   
    0.686
Kpol_1058p13
Uncharacterized protein.
   
    0.629
Kpol_1051p3
rRNA-processing protein; Involved in nucleolar integrity and required for processing of the pre-rRNA for the 60S ribosome subunit. Belongs to the CGR1 family.
   
    0.613
Kpol_1012p8
Ribosome biogenesis protein NOP53; May play a role in ribosome biogenesis. Belongs to the NOP53 family.
   
    0.605
DBP9
ATP-dependent RNA helicase DBP9; ATP-binding RNA helicase involved in the biogenesis of 60S ribosomal subunits and is required for the normal formation of 25S and 5.8S rRNAs; Belongs to the DEAD box helicase family. DDX56/DBP9 subfamily.
   
   0.602
Kpol_1045p74
Uncharacterized protein.
   
    0.597
Kpol_1029p3
RRM domain-containing protein.
   
    0.588
ROK1
ATP-dependent RNA helicase ROK1; ATP-dependent RNA helicase involved in 40S ribosomal subunit biogenesis. Required for the processing and cleavage of 35S pre-rRNA at sites A0, A1, and A2, leading to mature 18S rRNA.
   
    0.560
Your Current Organism:
Vanderwaltozyma polyspora
NCBI taxonomy Id: 436907
Other names: V. polyspora DSM 70294, Vanderwaltozyma polyspora DSM 70294, Vanderwaltozyma polyspora DSMZ 70294
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.