STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SLX4Structure-specific endonuclease subunit SLX4; Regulatory subunit of the SLX1-SLX4 structure-specific endonuclease that resolves DNA secondary structures generated during DNA repair and recombination. Has endonuclease activity towards branched DNA substrates, introducing single-strand cuts in duplex DNA close to junctions with ss-DNA. (680 aa)    
Predicted Functional Partners:
SLX1
Structure-specific endonuclease subunit SLX1; Catalytic subunit of the SLX1-SLX4 structure-specific endonuclease that resolves DNA secondary structures generated during DNA repair and recombination. Has endonuclease activity towards branched DNA substrates, introducing single-strand cuts in duplex DNA close to junctions with ss-DNA.
    
 0.986
Kpol_1050p63
Uncharacterized protein.
    
 
 0.948
Kpol_1018p31
Uncharacterized protein.
    
 
 0.691
Kpol_1060p23
Uncharacterized protein.
    
 
 0.691
Kpol_1007p11
ERCC4 domain-containing protein.
    
 
 0.688
Kpol_440p9
ERCC4 domain-containing protein.
    
 
 0.643
Kpol_1016p19
Uncharacterized protein.
    
 
 0.612
Kpol_301p4
Uncharacterized protein.
    
 
 0.611
Kpol_458p5
Uncharacterized protein.
    
 
 0.545
Kpol_1007p13
RMI1_N domain-containing protein.
    
 
 0.490
Your Current Organism:
Vanderwaltozyma polyspora
NCBI taxonomy Id: 436907
Other names: V. polyspora DSM 70294, Vanderwaltozyma polyspora DSM 70294, Vanderwaltozyma polyspora DSMZ 70294
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.