LOC109959772 protein (Monopterus albus) - STRING interaction network

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

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Score

LOC109959772

Si:dkey-3h3.3. (429 aa)

Predicted Functional Partners:

notch1

0.916

LOC109973052

0.911

LOC109961482

0.813

ENSMALP00000005859

0.675

LOC109953969

0.664

ENSMALP00000005797

0.664

ENSMALP00000032881

0.664

ifih1

0.525

mib2

0.441

ube2l3

0.440

Your Current Organism:

Monopterus albus

NCBI taxonomy Id: 43700
Other names: Fluta alba, M. albus, Muraena alba, rice-field eel, swamp eel

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structured XML interaction data, according to the 'PSI-MI' data standard

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... protein annotations:

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... functional annotations:

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSMALP00000005797	ENSMALP00000005859	ENSMALP00000005797	ENSMALP00000005859	Poly [ADP-ribose] polymerase.	Uncharacterized protein.	0.423
ENSMALP00000005797	LOC109953969	ENSMALP00000005797	ENSMALP00000005629	Poly [ADP-ribose] polymerase.	Macro domain-containing protein.	0.899
ENSMALP00000005797	LOC109959772	ENSMALP00000005797	ENSMALP00000010185	Poly [ADP-ribose] polymerase.	Si:dkey-3h3.3.	0.664
ENSMALP00000005797	LOC109961482	ENSMALP00000005797	ENSMALP00000008756	Poly [ADP-ribose] polymerase.	Family with sequence similarity 162 member A.	0.475
ENSMALP00000005797	ifih1	ENSMALP00000005797	ENSMALP00000022170	Poly [ADP-ribose] polymerase.	Interferon induced with helicase C domain 1.	0.626
ENSMALP00000005859	ENSMALP00000005797	ENSMALP00000005859	ENSMALP00000005797	Uncharacterized protein.	Poly [ADP-ribose] polymerase.	0.423
ENSMALP00000005859	LOC109959772	ENSMALP00000005859	ENSMALP00000010185	Uncharacterized protein.	Si:dkey-3h3.3.	0.675
ENSMALP00000005859	LOC109961482	ENSMALP00000005859	ENSMALP00000008756	Uncharacterized protein.	Family with sequence similarity 162 member A.	0.474
ENSMALP00000032881	LOC109959772	ENSMALP00000032881	ENSMALP00000010185	Uncharacterized protein.	Si:dkey-3h3.3.	0.664
ENSMALP00000032881	LOC109961482	ENSMALP00000032881	ENSMALP00000008756	Uncharacterized protein.	Family with sequence similarity 162 member A.	0.475
ENSMALP00000032881	ifih1	ENSMALP00000032881	ENSMALP00000022170	Uncharacterized protein.	Interferon induced with helicase C domain 1.	0.626
LOC109953969	ENSMALP00000005797	ENSMALP00000005629	ENSMALP00000005797	Macro domain-containing protein.	Poly [ADP-ribose] polymerase.	0.899
LOC109953969	LOC109959772	ENSMALP00000005629	ENSMALP00000010185	Macro domain-containing protein.	Si:dkey-3h3.3.	0.664
LOC109953969	LOC109961482	ENSMALP00000005629	ENSMALP00000008756	Macro domain-containing protein.	Family with sequence similarity 162 member A.	0.475
LOC109953969	ifih1	ENSMALP00000005629	ENSMALP00000022170	Macro domain-containing protein.	Interferon induced with helicase C domain 1.	0.626
LOC109959772	ENSMALP00000005797	ENSMALP00000010185	ENSMALP00000005797	Si:dkey-3h3.3.	Poly [ADP-ribose] polymerase.	0.664
LOC109959772	ENSMALP00000005859	ENSMALP00000010185	ENSMALP00000005859	Si:dkey-3h3.3.	Uncharacterized protein.	0.675
LOC109959772	ENSMALP00000032881	ENSMALP00000010185	ENSMALP00000032881	Si:dkey-3h3.3.	Uncharacterized protein.	0.664
LOC109959772	LOC109953969	ENSMALP00000010185	ENSMALP00000005629	Si:dkey-3h3.3.	Macro domain-containing protein.	0.664
LOC109959772	LOC109961482	ENSMALP00000010185	ENSMALP00000008756	Si:dkey-3h3.3.	Family with sequence similarity 162 member A.	0.813

page 1 of 3

Network Stats

number of nodes:

11

number of edges:

35

average node degree:

6.36

avg. local clustering coefficient:

0.876

expected number of edges:

12

PPI enrichment p-value:

1.09e-07

your network has significantly more interactions
than expected (what does that mean?)

Functional enrichments in your networkNote: some enrichments may be expected here (why?)
disable highlight explain columns

Biological Process (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0006457

Protein folding

6 of 16

2.07

3.55

1.75e-08

Molecular Function (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0051082

Unfolded protein binding

5 of 8

2.29

3.5

9.88e-08

GO:0005515

Protein binding

6 of 47

1.6

2.2

1.47e-06

GO:0140662

ATP-dependent protein folding chaperone

2 of 4

2.19

0.97

0.0154

GO:1901363

Heterocyclic compound binding

10 of 966

0.51

0.39

0.0046

GO:0097159

Organic cyclic compound binding

10 of 966

0.51

0.39

0.0046

(more ...)

Local Network Cluster (STRING)

cluster

description

count in network

strength

signal

false discovery rate

CL:404

Unfolded protein binding, and Chaperone binding

6 of 8

2.37

4.73

2.40e-10

CL:400

Mixed, incl. Chaperone, and Unfolded protein binding

7 of 24

1.96

3.98

2.40e-10

CL:83

Gene expression, and Bacterial secretion system

11 of 185

1.27

2.07

1.28e-11

CL:174

Elongation factor Tu domain 2, and Small ribosomal subunit

2 of 6

2.02

0.9

0.0204

CL:118

Structural constituent of ribosome

3 of 34

1.44

0.81

0.0177

(more ...)

Subcellular Localization (COMPARTMENTS)

compartment

description

count in network

strength

signal

false discovery rate

GOCC:0042603

Capsule

2 of 2

2.49

1.01

0.0142

GOCC:0015934

Large ribosomal subunit

2 of 7

1.95

0.82

0.0282

Annotated Keywords (UniProt)

keyword

description

count in network

strength

signal

false discovery rate

KW-0346

Stress response

3 of 11

1.93

1.4

0.0017

KW-0143

Chaperone

3 of 12

1.89

1.38

0.0017

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