STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
LOC109951445Cyclin-dependent kinase 5 activator. (335 aa)    
Predicted Functional Partners:
cdk5
Cyclin-dependent kinase 5.
    
 0.910
LOC109959052
Macrophage stimulating 1 receptor a.
   
  0.518
mst1r
Macrophage stimulating 1 receptor b.
   
  0.518
met
MET proto-oncogene, receptor tyrosine kinase.
   
  0.518
nrp1
Neuropilin; Belongs to the neuropilin family.
   
 
  0.457
tp73
Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family.
     
 0.418
gsk3b
Glycogen synthase kinase 3 beta, genome duplicate b; Belongs to the protein kinase superfamily.
    
  0.415
LOC109970724
Glycogen synthase kinase 3 alpha a; Belongs to the protein kinase superfamily.
    
  0.415
gsk3a
Glycogen synthase kinase 3 alpha b; Belongs to the protein kinase superfamily.
    
  0.415
Your Current Organism:
Monopterus albus
NCBI taxonomy Id: 43700
Other names: Fluta alba, M. albus, Muraena alba, rice-field eel, swamp eel
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