STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
LOC109957854Coagulation factor VIII, procoagulant component; Belongs to the multicopper oxidase family. (1632 aa)    
Predicted Functional Partners:
f2
Prothrombin; Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing; Belongs to the peptidase S1 family.
    
 0.889
pros1
Protein S.
   
 0.726
mcfd2
Multiple coagulation factor deficiency 2.
     
 0.704
lman1
Lectin, mannose-binding, 1.
    
 0.683
serpine2
Serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2; Belongs to the serpin family.
    
 0.657
serpinc1
Serpin peptidase inhibitor, clade C (antithrombin), member 1; Belongs to the serpin family.
   
 0.652
ctsc
Cathepsin C; Belongs to the peptidase C1 family.
   
 
 0.630
ENSMALP00000002687
VWFD domain-containing protein.
    
 0.622
ENSMALP00000007815
Uncharacterized protein.
    
 0.622
vwf
Von Willebrand factor.
    
 0.622
Your Current Organism:
Monopterus albus
NCBI taxonomy Id: 43700
Other names: Fluta alba, M. albus, Muraena alba, rice-field eel, swamp eel
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