rp2 protein (Monopterus albus) - STRING interaction network

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Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

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gene co-occurrence

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rp2

Protein XRP2; Acts as a GTPase-activating protein (GAP) for tubulin in concert with tubulin-specific chaperone C, but does not enhance tubulin heterodimerization. (365 aa)

Predicted Functional Partners:

arl3

0.980

LOC109973175

0.858

LOC109955948

0.748

unc119b

0.748

tbcd

0.683

nphp3

0.678

tbce

0.676

LOC109960244

0.634

UNC119

0.634

LOC109968148

0.620

Your Current Organism:

Monopterus albus

NCBI taxonomy Id: 43700
Other names: Fluta alba, M. albus, Muraena alba, rice-field eel, swamp eel

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
LOC109955948	LOC109973175	ENSMALP00000001822	ENSMALP00000020069	GMP_PDE_delta domain-containing protein.	ADP ribosylation factor like GTPase 3, like 2; Belongs to the small GTPase superfamily. Arf family.	0.685
LOC109955948	arl3	ENSMALP00000001822	ENSMALP00000007540	GMP_PDE_delta domain-containing protein.	ADP ribosylation factor like GTPase 3b; Belongs to the small GTPase superfamily. Arf family.	0.765
LOC109955948	nphp3	ENSMALP00000001822	ENSMALP00000011507	GMP_PDE_delta domain-containing protein.	Nephronophthisis 3.	0.712
LOC109955948	rp2	ENSMALP00000001822	ENSMALP00000021548	GMP_PDE_delta domain-containing protein.	Protein XRP2; Acts as a GTPase-activating protein (GAP) for tubulin in concert with tubulin-specific chaperone C, but does not enhance tubulin heterodimerization.	0.748
LOC109960244	LOC109973175	ENSMALP00000004483	ENSMALP00000020069	GMP_PDE_delta domain-containing protein.	ADP ribosylation factor like GTPase 3, like 2; Belongs to the small GTPase superfamily. Arf family.	0.877
LOC109960244	arl3	ENSMALP00000004483	ENSMALP00000007540	GMP_PDE_delta domain-containing protein.	ADP ribosylation factor like GTPase 3b; Belongs to the small GTPase superfamily. Arf family.	0.944
LOC109960244	nphp3	ENSMALP00000004483	ENSMALP00000011507	GMP_PDE_delta domain-containing protein.	Nephronophthisis 3.	0.599
LOC109960244	rp2	ENSMALP00000004483	ENSMALP00000021548	GMP_PDE_delta domain-containing protein.	Protein XRP2; Acts as a GTPase-activating protein (GAP) for tubulin in concert with tubulin-specific chaperone C, but does not enhance tubulin heterodimerization.	0.634
LOC109968148	rp2	ENSMALP00000000251	ENSMALP00000021548	Uncharacterized protein.	Protein XRP2; Acts as a GTPase-activating protein (GAP) for tubulin in concert with tubulin-specific chaperone C, but does not enhance tubulin heterodimerization.	0.620
LOC109973175	LOC109955948	ENSMALP00000020069	ENSMALP00000001822	ADP ribosylation factor like GTPase 3, like 2; Belongs to the small GTPase superfamily. Arf family.	GMP_PDE_delta domain-containing protein.	0.685
LOC109973175	LOC109960244	ENSMALP00000020069	ENSMALP00000004483	ADP ribosylation factor like GTPase 3, like 2; Belongs to the small GTPase superfamily. Arf family.	GMP_PDE_delta domain-containing protein.	0.877
LOC109973175	UNC119	ENSMALP00000020069	ENSMALP00000025484	ADP ribosylation factor like GTPase 3, like 2; Belongs to the small GTPase superfamily. Arf family.	Unc-119 lipid binding chaperone.	0.877
LOC109973175	rp2	ENSMALP00000020069	ENSMALP00000021548	ADP ribosylation factor like GTPase 3, like 2; Belongs to the small GTPase superfamily. Arf family.	Protein XRP2; Acts as a GTPase-activating protein (GAP) for tubulin in concert with tubulin-specific chaperone C, but does not enhance tubulin heterodimerization.	0.858
LOC109973175	unc119b	ENSMALP00000020069	ENSMALP00000025608	ADP ribosylation factor like GTPase 3, like 2; Belongs to the small GTPase superfamily. Arf family.	Unc-119 homolog 1.	0.685
UNC119	LOC109973175	ENSMALP00000025484	ENSMALP00000020069	Unc-119 lipid binding chaperone.	ADP ribosylation factor like GTPase 3, like 2; Belongs to the small GTPase superfamily. Arf family.	0.877
UNC119	arl3	ENSMALP00000025484	ENSMALP00000007540	Unc-119 lipid binding chaperone.	ADP ribosylation factor like GTPase 3b; Belongs to the small GTPase superfamily. Arf family.	0.944
UNC119	nphp3	ENSMALP00000025484	ENSMALP00000011507	Unc-119 lipid binding chaperone.	Nephronophthisis 3.	0.599
UNC119	rp2	ENSMALP00000025484	ENSMALP00000021548	Unc-119 lipid binding chaperone.	Protein XRP2; Acts as a GTPase-activating protein (GAP) for tubulin in concert with tubulin-specific chaperone C, but does not enhance tubulin heterodimerization.	0.634
arl3	LOC109955948	ENSMALP00000007540	ENSMALP00000001822	ADP ribosylation factor like GTPase 3b; Belongs to the small GTPase superfamily. Arf family.	GMP_PDE_delta domain-containing protein.	0.765
arl3	LOC109960244	ENSMALP00000007540	ENSMALP00000004483	ADP ribosylation factor like GTPase 3b; Belongs to the small GTPase superfamily. Arf family.	GMP_PDE_delta domain-containing protein.	0.944

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Network Stats

number of nodes:

11

number of edges:

55

average node degree:

10

avg. local clustering coefficient:

1

expected number of edges:

14

PPI enrichment p-value:

1.11e-16

your network has significantly more interactions
than expected (what does that mean?)

Functional enrichments in your networkNote: some enrichments may be expected here (why?)
disable highlight explain columns

Biological Process (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0006412

Translation

10 of 103

1.39

2.4

8.86e-11

GO:0044238

Primary metabolic process

11 of 1033

0.43

0.36

0.0011

Molecular Function (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0003735

Structural constituent of ribosome

9 of 53

1.63

3.29

2.17e-11

GO:0070180

Large ribosomal subunit rRNA binding

2 of 2

2.4

1.09

0.0098

GO:0019843

rRNA binding

4 of 40

1.4

1.07

0.0029

GO:0003723

RNA binding

5 of 89

1.15

0.89

0.0029

Cellular Component (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0005840

Ribosome

9 of 56

1.61

3.29

6.22e-12

GO:0044391

Ribosomal subunit

5 of 14

1.96

3.18

6.49e-08

GO:0015934

Large ribosomal subunit

3 of 8

1.98

1.97

9.75e-05

GO:0015935

Small ribosomal subunit

2 of 6

1.93

1.24

0.0038

GO:0005622

Intracellular anatomical structure

11 of 972

0.46

0.4

0.00011

Local Network Cluster (STRING)

cluster

description

count in network

strength

signal

false discovery rate

CL:103

Ribosomal protein

10 of 65

1.59

3.36

7.11e-13

CL:107

Ribosomal protein

9 of 58

1.6

3.22

8.40e-12

CL:110

Ribosomal protein

8 of 51

1.6

3.01

2.01e-10

CL:112

Ribosomal protein

7 of 45

1.6

2.71

7.76e-09

CL:155

Structural constituent of ribosome

4 of 16

1.8

2.07

2.61e-05

(more ...)

KEGG Pathways

pathway

description

count in network

strength

signal

false discovery rate

map03010

Ribosome

9 of 55

1.62

3.32

6.37e-12

Subcellular Localization (COMPARTMENTS)

compartment

description

count in network

strength

signal

false discovery rate

GOCC:0005840

Ribosome

7 of 40

1.65

2.76

1.68e-08

GOCC:0044391

Ribosomal subunit

4 of 16

1.8

2.09

2.30e-05

GOCC:0015935

Small ribosomal subunit

3 of 9

1.93

1.74

0.00028

GOCC:0043229

Intracellular organelle

10 of 270

0.97

1.14

9.78e-08

GOCC:0022627

Cytosolic small ribosomal subunit

2 of 7

1.86

1.0

0.0114

(more ...)

Annotated Keywords (UniProt)

keyword

description

count in network

strength

signal

false discovery rate

KW-0689

Ribosomal protein

9 of 54

1.63

3.33

8.02e-12

KW-0699

rRNA-binding

4 of 38

1.43

1.25

0.00083

KW-0810

Translation regulation

2 of 5

2.01

1.03

0.0108

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