node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
LOC109959580 | sirt2 | ENSMALP00000029515 | ENSMALP00000029546 | Uncoupling protein 3; Belongs to the mitochondrial carrier (TC 2.A.29) family. | NAD-dependent protein deacetylase; NAD-dependent protein deacetylase. | 0.449 |
LOC109959580 | sirt4 | ENSMALP00000029515 | ENSMALP00000030449 | Uncoupling protein 3; Belongs to the mitochondrial carrier (TC 2.A.29) family. | NAD-dependent protein deacylase; NAD-dependent protein deacylase. Catalyzes the NAD-dependent hydrolysis of acyl groups from lysine residues; Belongs to the sirtuin family. Class II subfamily. | 0.585 |
LOC109959580 | sirt5 | ENSMALP00000029515 | ENSMALP00000000145 | Uncoupling protein 3; Belongs to the mitochondrial carrier (TC 2.A.29) family. | NAD-dependent protein deacylase sirtuin-5, mitochondrial; NAD-dependent lysine demalonylase, desuccinylase and deglutarylase that specifically removes malonyl, succinyl and glutaryl groups on target proteins. Has weak NAD-dependent protein deacetylase activity; however this activity may not be physiologically relevant in vivo. | 0.445 |
LOC109959580 | sirt6 | ENSMALP00000029515 | ENSMALP00000030932 | Uncoupling protein 3; Belongs to the mitochondrial carrier (TC 2.A.29) family. | Sirtuin 6. | 0.449 |
sirt2 | LOC109959580 | ENSMALP00000029546 | ENSMALP00000029515 | NAD-dependent protein deacetylase; NAD-dependent protein deacetylase. | Uncoupling protein 3; Belongs to the mitochondrial carrier (TC 2.A.29) family. | 0.449 |
sirt2 | sirt4 | ENSMALP00000029546 | ENSMALP00000030449 | NAD-dependent protein deacetylase; NAD-dependent protein deacetylase. | NAD-dependent protein deacylase; NAD-dependent protein deacylase. Catalyzes the NAD-dependent hydrolysis of acyl groups from lysine residues; Belongs to the sirtuin family. Class II subfamily. | 0.675 |
sirt2 | sirt5 | ENSMALP00000029546 | ENSMALP00000000145 | NAD-dependent protein deacetylase; NAD-dependent protein deacetylase. | NAD-dependent protein deacylase sirtuin-5, mitochondrial; NAD-dependent lysine demalonylase, desuccinylase and deglutarylase that specifically removes malonyl, succinyl and glutaryl groups on target proteins. Has weak NAD-dependent protein deacetylase activity; however this activity may not be physiologically relevant in vivo. | 0.650 |
sirt2 | sirt6 | ENSMALP00000029546 | ENSMALP00000030932 | NAD-dependent protein deacetylase; NAD-dependent protein deacetylase. | Sirtuin 6. | 0.455 |
sirt4 | LOC109959580 | ENSMALP00000030449 | ENSMALP00000029515 | NAD-dependent protein deacylase; NAD-dependent protein deacylase. Catalyzes the NAD-dependent hydrolysis of acyl groups from lysine residues; Belongs to the sirtuin family. Class II subfamily. | Uncoupling protein 3; Belongs to the mitochondrial carrier (TC 2.A.29) family. | 0.585 |
sirt4 | sirt2 | ENSMALP00000030449 | ENSMALP00000029546 | NAD-dependent protein deacylase; NAD-dependent protein deacylase. Catalyzes the NAD-dependent hydrolysis of acyl groups from lysine residues; Belongs to the sirtuin family. Class II subfamily. | NAD-dependent protein deacetylase; NAD-dependent protein deacetylase. | 0.675 |
sirt4 | sirt5 | ENSMALP00000030449 | ENSMALP00000000145 | NAD-dependent protein deacylase; NAD-dependent protein deacylase. Catalyzes the NAD-dependent hydrolysis of acyl groups from lysine residues; Belongs to the sirtuin family. Class II subfamily. | NAD-dependent protein deacylase sirtuin-5, mitochondrial; NAD-dependent lysine demalonylase, desuccinylase and deglutarylase that specifically removes malonyl, succinyl and glutaryl groups on target proteins. Has weak NAD-dependent protein deacetylase activity; however this activity may not be physiologically relevant in vivo. | 0.505 |
sirt4 | sirt6 | ENSMALP00000030449 | ENSMALP00000030932 | NAD-dependent protein deacylase; NAD-dependent protein deacylase. Catalyzes the NAD-dependent hydrolysis of acyl groups from lysine residues; Belongs to the sirtuin family. Class II subfamily. | Sirtuin 6. | 0.749 |
sirt5 | LOC109959580 | ENSMALP00000000145 | ENSMALP00000029515 | NAD-dependent protein deacylase sirtuin-5, mitochondrial; NAD-dependent lysine demalonylase, desuccinylase and deglutarylase that specifically removes malonyl, succinyl and glutaryl groups on target proteins. Has weak NAD-dependent protein deacetylase activity; however this activity may not be physiologically relevant in vivo. | Uncoupling protein 3; Belongs to the mitochondrial carrier (TC 2.A.29) family. | 0.445 |
sirt5 | sirt2 | ENSMALP00000000145 | ENSMALP00000029546 | NAD-dependent protein deacylase sirtuin-5, mitochondrial; NAD-dependent lysine demalonylase, desuccinylase and deglutarylase that specifically removes malonyl, succinyl and glutaryl groups on target proteins. Has weak NAD-dependent protein deacetylase activity; however this activity may not be physiologically relevant in vivo. | NAD-dependent protein deacetylase; NAD-dependent protein deacetylase. | 0.650 |
sirt5 | sirt4 | ENSMALP00000000145 | ENSMALP00000030449 | NAD-dependent protein deacylase sirtuin-5, mitochondrial; NAD-dependent lysine demalonylase, desuccinylase and deglutarylase that specifically removes malonyl, succinyl and glutaryl groups on target proteins. Has weak NAD-dependent protein deacetylase activity; however this activity may not be physiologically relevant in vivo. | NAD-dependent protein deacylase; NAD-dependent protein deacylase. Catalyzes the NAD-dependent hydrolysis of acyl groups from lysine residues; Belongs to the sirtuin family. Class II subfamily. | 0.505 |
sirt5 | sirt6 | ENSMALP00000000145 | ENSMALP00000030932 | NAD-dependent protein deacylase sirtuin-5, mitochondrial; NAD-dependent lysine demalonylase, desuccinylase and deglutarylase that specifically removes malonyl, succinyl and glutaryl groups on target proteins. Has weak NAD-dependent protein deacetylase activity; however this activity may not be physiologically relevant in vivo. | Sirtuin 6. | 0.662 |
sirt6 | LOC109959580 | ENSMALP00000030932 | ENSMALP00000029515 | Sirtuin 6. | Uncoupling protein 3; Belongs to the mitochondrial carrier (TC 2.A.29) family. | 0.449 |
sirt6 | sirt2 | ENSMALP00000030932 | ENSMALP00000029546 | Sirtuin 6. | NAD-dependent protein deacetylase; NAD-dependent protein deacetylase. | 0.455 |
sirt6 | sirt4 | ENSMALP00000030932 | ENSMALP00000030449 | Sirtuin 6. | NAD-dependent protein deacylase; NAD-dependent protein deacylase. Catalyzes the NAD-dependent hydrolysis of acyl groups from lysine residues; Belongs to the sirtuin family. Class II subfamily. | 0.749 |
sirt6 | sirt5 | ENSMALP00000030932 | ENSMALP00000000145 | Sirtuin 6. | NAD-dependent protein deacylase sirtuin-5, mitochondrial; NAD-dependent lysine demalonylase, desuccinylase and deglutarylase that specifically removes malonyl, succinyl and glutaryl groups on target proteins. Has weak NAD-dependent protein deacetylase activity; however this activity may not be physiologically relevant in vivo. | 0.662 |