LOC109951291 protein (Monopterus albus) - STRING interaction network

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second shell of interactors

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Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

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co-expression

protein homology

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[Homology]

Score

LOC109951291

Flj13639. (329 aa)

Predicted Functional Partners:

LOC109965852

0.554

oxsm

0.522

mcat

0.484

FDX1

0.476

fdx2

0.476

rbp2

0.475

cd3e

0.460

LOC109959493

0.443

sord

0.405

Your Current Organism:

Monopterus albus

NCBI taxonomy Id: 43700
Other names: Fluta alba, M. albus, Muraena alba, rice-field eel, swamp eel

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
FDX1	LOC109951291	ENSMALP00000012347	ENSMALP00000031030	Ferredoxin 1.	Flj13639.	0.476
LOC109951291	FDX1	ENSMALP00000031030	ENSMALP00000012347	Flj13639.	Ferredoxin 1.	0.476
LOC109951291	LOC109959493	ENSMALP00000031030	ENSMALP00000028198	Flj13639.	Proteolipid protein 1b.	0.443
LOC109951291	LOC109965852	ENSMALP00000031030	ENSMALP00000001722	Flj13639.	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family.	0.554
LOC109951291	cd3e	ENSMALP00000031030	ENSMALP00000027741	Flj13639.	Ig_4 domain-containing protein.	0.460
LOC109951291	fdx2	ENSMALP00000031030	ENSMALP00000031066	Flj13639.	Ferredoxin 2.	0.476
LOC109951291	mcat	ENSMALP00000031030	ENSMALP00000015269	Flj13639.	Malonyl CoA:ACP acyltransferase (mitochondrial).	0.484
LOC109951291	oxsm	ENSMALP00000031030	ENSMALP00000027857	Flj13639.	3-oxoacyl-[acyl-carrier-protein] synthase; Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.	0.522
LOC109951291	rbp2	ENSMALP00000031030	ENSMALP00000030277	Flj13639.	Retinol binding protein 2a, cellular; Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family.	0.475
LOC109951291	sord	ENSMALP00000031030	ENSMALP00000026871	Flj13639.	Sorbitol dehydrogenase.	0.405
LOC109959493	LOC109951291	ENSMALP00000028198	ENSMALP00000031030	Proteolipid protein 1b.	Flj13639.	0.443
LOC109959493	LOC109965852	ENSMALP00000028198	ENSMALP00000001722	Proteolipid protein 1b.	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family.	0.646
LOC109965852	LOC109951291	ENSMALP00000001722	ENSMALP00000031030	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family.	Flj13639.	0.554
LOC109965852	LOC109959493	ENSMALP00000001722	ENSMALP00000028198	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family.	Proteolipid protein 1b.	0.646
cd3e	LOC109951291	ENSMALP00000027741	ENSMALP00000031030	Ig_4 domain-containing protein.	Flj13639.	0.460
fdx2	LOC109951291	ENSMALP00000031066	ENSMALP00000031030	Ferredoxin 2.	Flj13639.	0.476
mcat	LOC109951291	ENSMALP00000015269	ENSMALP00000031030	Malonyl CoA:ACP acyltransferase (mitochondrial).	Flj13639.	0.484
mcat	oxsm	ENSMALP00000015269	ENSMALP00000027857	Malonyl CoA:ACP acyltransferase (mitochondrial).	3-oxoacyl-[acyl-carrier-protein] synthase; Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.	0.999
oxsm	LOC109951291	ENSMALP00000027857	ENSMALP00000031030	3-oxoacyl-[acyl-carrier-protein] synthase; Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.	Flj13639.	0.522
oxsm	mcat	ENSMALP00000027857	ENSMALP00000015269	3-oxoacyl-[acyl-carrier-protein] synthase; Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.	Malonyl CoA:ACP acyltransferase (mitochondrial).	0.999

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Network Stats

number of nodes:

11

number of edges:

39

average node degree:

7.09

avg. local clustering coefficient:

0.968

expected number of edges:

43

PPI enrichment p-value:

0.736

your network does not have significantly more
interactions than expected (what does that mean?)

Functional enrichments in your networkNote: some enrichments may be expected here (why?)
disable highlight explain columns

Cellular Component (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0030176

Integral component of endoplasmic reticulum membrane

3 of 132

1.63

0.79

0.0265

GO:0005615

Extracellular space

6 of 1087

1.02

0.69

0.0095

Local Network Cluster (STRING)

cluster

description

count in network

strength

signal

false discovery rate

CL:4709

Mixed, incl. Lipolysis stimulated receptor (LSR), and Kringle

6 of 10

3.05

6.91

1.44e-13

CL:4713

Kringle, and Establishment of epithelial cell apical/basal polarity

4 of 5

3.18

4.72

2.48e-09

CL:4690

Immunoglobulin C-2 Type, and Leucine rich repeat N-terminal domain

7 of 143

1.97

4.0

2.48e-10

CL:4409

MHC I, and MHC class I-like antigen recognition-like superfamily

2 of 6

2.8

1.44

0.0024

Annotated Keywords (UniProt)

keyword

description

count in network

strength

signal

false discovery rate

KW-0420

Kringle

3 of 19

2.47

2.27

5.53e-05

KW-0720

Serine protease

3 of 80

1.85

1.38

0.0016

KW-1015

Disulfide bond

6 of 1146

1.0

0.81

0.0016

KW-0245

EGF-like domain

3 of 226

1.4

0.8

0.0167

KW-0964

Secreted

3 of 242

1.37

0.79

0.0167

Protein Domains and Features (InterPro)

domain

description

count in network

strength

signal

false discovery rate

IPR038178

Kringle superfamily

3 of 19

2.47

1.77

0.00052

IPR000001

Kringle

3 of 19

2.47

1.77

0.00052

IPR013806

Kringle-like fold

3 of 28

2.31

1.74

0.00052

IPR003591

Leucine-rich repeat, typical subtype

5 of 199

1.68

1.6

0.00026

IPR001611

Leucine-rich repeat

5 of 270

1.54

1.4

0.00052

(more ...)

Protein Domains (SMART)

domain

description

count in network

strength

signal

false discovery rate

SM00130

Kringle domain

3 of 19

2.47

2.24

6.46e-05

SM00013

Leucine rich repeat N-terminal domain

4 of 117

1.81

1.88

8.90e-05

SM00370

Leucine-rich repeats, outliers

5 of 233

1.61

1.75

6.30e-05

SM00369

Leucine-rich repeats, typical (most populated) subfamily

4 of 160

1.67

1.62

0.00023

SM00020

Trypsin-like serine protease

3 of 97

1.77

1.25

0.0027

(more ...)

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