STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
KRG17779.1Hypothetical protein; Belongs to the UPF0149 family. (193 aa)    
Predicted Functional Partners:
zapA
Cell division protein ZapA; Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division.
  
  
 0.637
pepP
Xaa-Pro aminopeptidase.
     
 0.633
ubiI
2-octaprenylphenol hydroxylase.
     
 0.605
ubiH
2-octaprenyl-6-methoxyphenol hydroxylase.
     
 0.605
gcvT
Aminomethyltransferase; The glycine cleavage system catalyzes the degradation of glycine.
       0.542
gcvH
Glycine cleavage system H protein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
       0.484
KRG17739.1
Hypothetical protein.
  
     0.478
gcvPA
Putative glycine dehydrogenase (decarboxylating) subunit 1; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.
       0.449
smg
Hypothetical protein; Belongs to the Smg family.
  
     0.438
ribE
6,7-dimethyl-8-ribityllumazine synthase; Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2- butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin; Belongs to the DMRL synthase family.
   
    0.428
Your Current Organism:
Berkiella cookevillensis
NCBI taxonomy Id: 437022
Other names: C. Berkiella cookevillensis, Candidatus Berkiella cookevillensis, Coxiellaceae bacterium CC99, Legionella-like amoebal pathogen CC99
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.