STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ORL35088.1Derived by automated computational analysis using gene prediction method: Protein Homology. (1086 aa)    
Predicted Functional Partners:
pnp
Polyribonucleotide nucleotidyltransferase; Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'- direction.
  
 
 0.990
eno
Phosphopyruvate hydratase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family.
   
 
 0.854
ORL35660.1
Oligoribonuclease; 3'-to-5' exoribonuclease specific for small oligoribonucleotides.
  
  
 0.840
ORL31929.1
RNase adaptor protein RapZ; Displays ATPase and GTPase activities.
   
 
 0.816
rph
Ribonuclease PH; Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation.
  
  
 0.805
rnj
Ribonuclease J; An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and/or decay.
     
 0.775
infA
Translation initiation factor IF-1; One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.
  
  
 0.761
rplU
50S ribosomal protein L21; This protein binds to 23S rRNA in the presence of protein L20; Belongs to the bacterial ribosomal protein bL21 family.
  
    0.716
ORL31425.1
Single-stranded DNA-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.701
ORL30874.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the UPF0109 family.
  
 
 
 0.700
Your Current Organism:
Rhodococcus hoagii
NCBI taxonomy Id: 43767
Other names: ATCC 14887 [[Nocardia restricta]], ATCC 25729 [[Rhodococcus equi]], ATCC 6939 [[Rhodococcus equi]], ATCC 7005 [[Corynebacterium hoagii]], Bacillus hoagii, CCUG 17758 [[Nocardia restricta]], CCUG 20991 [[Corynebacterium hoagii]], CCUG 892 [[Rhodococcus equi]], CIP 54.72 [[Rhodococcus equi]], CIP 81.17 [[Corynebacterium hoagii]], Corynebacterium (pyogenes) equi roseum, Corynebacterium hoagii, Corynebacterium magnusson-holth, Corynebacterium purulentus, Corynebacterium pyogenes (equi), DSM 20295 [[Corynebacterium hoagii]], DSM 20307 [[Rhodococcus equi]], DSM 43199 [[Nocardia restricta]], HAMBI 2061 [[Rhodococcus equi]], IFO 14956 [[Rhodococcus equi]], JCM 3209 [[Rhodococcus equi]], JCM 3223 [[Nocardia restricta]], LMG 18452 [[Rhodococcus equi]], LMG 7335 [[Nocardia restricta]], LMG:18452 [[Rhodococcus equi]], LMG:7335 [[Nocardia restricta]], Mycobacterium equi, Mycobacterium restrictum, NBRC 101255 [[Rhodococcus equi]], NBRC 103062 [[Corynebacterium hoagii]], NBRC 14956 [[Rhodococcus equi]], NCTC 10673 [[Corynebacterium hoagii]], NRRL B-16538 [[Rhodococcus equi]], Nocardia restricta, Prescottella equi, Prescottia equi, Proactinomyces restrictus, R. hoagii, Rhodococcus equi, VKM Ac-953 [[Rhodococcus equi]]
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