STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
gndPhosphogluconate dehydrogenase (NADP(+)-dependent, decarboxylating); Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH. (486 aa)    
Predicted Functional Partners:
zwf
Glucose-6-phosphate dehydrogenase; Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone.
 
 0.996
aroK-2
Gluconokinase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 0.994
pgl
6-phosphogluconolactonase; Hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate.
 
 
 0.967
rpe
Ribulose-phosphate 3-epimerase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the ribulose-phosphate 3-epimerase family.
   
 0.955
RpiB
Ribose-5-phosphate isomerase; Catalyzes the interconversion of ribose 5-phosphate to ribulose 5-phosphate; enzyme from E. coli shows allose 6-phosphate isomerase activity; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
 0.920
gnd-2
6-phosphogluconate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 
0.918
tkt
Transketolase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the transketolase family.
  
 
 0.878
tal
Transaldolase; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway; Belongs to the transaldolase family. Type 2 subfamily.
  
 
 0.872
pgi
Glucose-6-phosphate isomerase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the GPI family.
  
  
 0.747
GuaB1
Guanosine monophosphate reductase; Catalyzes the synthesis of xanthosine monophosphate by the NAD+ dependent oxidation of inosine monophosphate; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
 0.614
Your Current Organism:
Rhodococcus hoagii
NCBI taxonomy Id: 43767
Other names: ATCC 14887 [[Nocardia restricta]], ATCC 25729 [[Rhodococcus equi]], ATCC 6939 [[Rhodococcus equi]], ATCC 7005 [[Corynebacterium hoagii]], Bacillus hoagii, CCUG 17758 [[Nocardia restricta]], CCUG 20991 [[Corynebacterium hoagii]], CCUG 892 [[Rhodococcus equi]], CIP 54.72 [[Rhodococcus equi]], CIP 81.17 [[Corynebacterium hoagii]], Corynebacterium (pyogenes) equi roseum, Corynebacterium hoagii, Corynebacterium magnusson-holth, Corynebacterium purulentus, Corynebacterium pyogenes (equi), DSM 20295 [[Corynebacterium hoagii]], DSM 20307 [[Rhodococcus equi]], DSM 43199 [[Nocardia restricta]], HAMBI 2061 [[Rhodococcus equi]], IFO 14956 [[Rhodococcus equi]], JCM 3209 [[Rhodococcus equi]], JCM 3223 [[Nocardia restricta]], LMG 18452 [[Rhodococcus equi]], LMG 7335 [[Nocardia restricta]], LMG:18452 [[Rhodococcus equi]], LMG:7335 [[Nocardia restricta]], Mycobacterium equi, Mycobacterium restrictum, NBRC 101255 [[Rhodococcus equi]], NBRC 103062 [[Corynebacterium hoagii]], NBRC 14956 [[Rhodococcus equi]], NCTC 10673 [[Corynebacterium hoagii]], NRRL B-16538 [[Rhodococcus equi]], Nocardia restricta, Prescottella equi, Prescottia equi, Proactinomyces restrictus, R. hoagii, Rhodococcus equi, VKM Ac-953 [[Rhodococcus equi]]
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