STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
pyrHUnannotated protein; Catalyzes the reversible phosphorylation of UMP to UDP. (246 aa)    
Predicted Functional Partners:
frr
Unannotated protein; Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another; Belongs to the RRF family.
 
  
 0.987
tsf
Unannotated protein; Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome. Belongs to the EF-Ts family.
 
  
 0.977
rpsB
Unannotated protein; Belongs to the universal ribosomal protein uS2 family.
  
 
 0.970
upp
Unannotated protein; Catalyzes the conversion of uracil and 5-phospho-alpha-D- ribose 1-diphosphate (PRPP) to UMP and diphosphate.
   
 
 0.945
pyrF
Unannotated protein; Belongs to the OMP decarboxylase family. Type 2 subfamily.
   
 
 0.933
ndk
Unannotated protein; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family.
   
 
 0.921
pyrR
Unannotated protein; Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant.
     
 0.915
DI558_08435
Unannotated protein; GTPase that plays an essential role in the late steps of ribosome biogenesis.
 
 
 0.905
nrdE
Unannotated protein; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.
   
 
 0.902
adk
Unannotated protein; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family.
  
 
 0.862
Your Current Organism:
Corynebacterium propinquum
NCBI taxonomy Id: 43769
Other names: ATCC 51488, C. propinquum, CCUG 33048, CDC coryneform group ANF-3, CIP 103792, DSM 44285, JCM 12106, strain B 77159
Server load: low (12%) [HD]