STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SEM13587.1Spermidine/putrescine transport system substrate-binding protein. (367 aa)    
Predicted Functional Partners:
SEM74410.1
Tungstate transport system ATP-binding protein; Belongs to the ABC transporter superfamily.
  
 
 0.963
speE
Spermidine synthase; Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy-AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine.
  
  
 0.598
topA
DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...]
     
 0.561
SEM13679.1
Amino acid ABC transporter substrate-binding protein, PAAT family; Belongs to the bacterial solute-binding protein 3 family.
 
  
 0.543
SEM52632.1
Threonine/homoserine/homoserine lactone efflux protein.
  
     0.517
SEM13597.1
Hypothetical protein.
       0.510
SEM13570.1
Hypothetical protein.
       0.500
SEM13617.1
Ethanolamine ammonia-lyase light chain.
 
     0.447
SEM68379.1
NitT/TauT family transport system ATP-binding protein.
    
  0.431
SEM13545.1
Predicted PurR-regulated permease PerM.
     
 0.424
Your Current Organism:
Syntrophus gentianae
NCBI taxonomy Id: 43775
Other names: CIP 105111, DSM 8423, S. gentianae, strain HQG1
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