STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SEM20187.1Conserved hypothetical protein, cofD-related. (732 aa)    
Predicted Functional Partners:
SEM26267.1
UPF0042 nucleotide-binding protein; Displays ATPase and GTPase activities.
  
  
 0.894
SEM65988.1
Protein phosphatase.
  
  
 0.784
SEM11888.1
Electron transport complex protein RnfG.
  
     0.752
SEM58473.1
Multimeric flavodoxin WrbA.
  
     0.708
SEM04499.1
Response regulator receiver domain-containing protein.
  
     0.659
SEM43222.1
Alpha/beta hydrolase family protein.
  
     0.656
SEM67371.1
Methyltransferase domain-containing protein.
  
     0.606
SEM31088.1
Hypothetical protein; Belongs to the UPF0250 family.
  
     0.602
topA
DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...]
   
   0.598
SEM20207.1
UDP-N-acetylglucosamine/UDP-N- acetylgalactosaminediphosphorylase.
     
 0.577
Your Current Organism:
Syntrophus gentianae
NCBI taxonomy Id: 43775
Other names: CIP 105111, DSM 8423, S. gentianae, strain HQG1
Server load: low (16%) [HD]