STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
tilStRNA(Ile)-lysidine synthase; Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine. Belongs to the tRNA(Ile)-lysidine synthase family. (476 aa)    
Predicted Functional Partners:
SEM56316.1
Hypoxanthine phosphoribosyltransferase; Belongs to the purine/pyrimidine phosphoribosyltransferase family.
 
 0.954
guaA
GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP.
  
 
 0.897
guaB
Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.
  
 
  0.847
tadA
tRNA-adenosine deaminase; Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2); Belongs to the cytidine and deoxycytidylate deaminase family.
 
 
 0.839
carB-2
Carbamoyl-phosphate synthase large subunit; Belongs to the CarB family.
  
  0.832
SEM43306.1
Sulfur carrier protein.
  
 
 0.832
SEM42771.1
Mannose-1-phosphate guanylyltransferase (GDP); Belongs to the mannose-6-phosphate isomerase type 2 family.
    
  0.779
SEM31299.1
Phosphoglycolate phosphatase.
       0.731
SEM60930.1
tRNA threonylcarbamoyladenosine biosynthesis protein TsaB.
 
   
 0.727
SEM31401.1
tRNA threonylcarbamoyladenosine biosynthesis protein TsaE.
 
   
 0.711
Your Current Organism:
Syntrophus gentianae
NCBI taxonomy Id: 43775
Other names: CIP 105111, DSM 8423, S. gentianae, strain HQG1
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