STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SEM45331.1Hydrogenase maturation protein HypC. (76 aa)    
Predicted Functional Partners:
SEM45310.1
Hydrogenase maturation protein HypD; Belongs to the HypD family.
 
 
 0.999
SEM45257.1
Hydrogenase maturation protein, carbamoyl dehydratase HypE.
 
 
 0.995
SEM45294.1
Hydrogenase nickel incorporation protein HypB.
 
  
 0.987
SEM45277.1
Hydrogenase maturation protein, carbamoyltransferase HypF; Involved in the maturation of [NiFe] hydrogenases. Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of [NiFe]-hydrogenases. HypF functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide.
 
 
 0.965
hypA
Hydrogenase-3 nickel incorporation protein HypA; Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase.
 
  
 0.933
SEM45399.1
[NiFe]-hydrogenase I apoprotein, large subunit; Belongs to the [NiFe]/[NiFeSe] hydrogenase large subunit family.
 
 
 0.910
SEM45422.1
[NiFe] hydrogenase small subunit.
 
 
 0.835
SEM45364.1
Hydrogenase maturation protease.
 
  
 0.827
SEM45383.1
[NiFe]-hydrogenase I apocytochrome b subunit.
 
  
 0.715
SEM18527.1
NAD(P)-dependent nickel-iron dehydrogenase catalytic subunit; Belongs to the [NiFe]/[NiFeSe] hydrogenase large subunit family.
 
   
 0.550
Your Current Organism:
Syntrophus gentianae
NCBI taxonomy Id: 43775
Other names: CIP 105111, DSM 8423, S. gentianae, strain HQG1
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