node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
H3K5H5_9FIRM | H3K883_9FIRM | GCA_900128435_00056 | GCA_900128435_01750 | Uracil-xanthine permease. | Uncharacterized protein. | 0.556 |
H3K5H5_9FIRM | carA | GCA_900128435_00056 | GCA_900128435_00613 | Uracil-xanthine permease. | Carbamoyl-phosphate synthase small chain; Belongs to the CarA family. | 0.803 |
H3K5H5_9FIRM | carB | GCA_900128435_00056 | GCA_900128435_00612 | Uracil-xanthine permease. | Carbamoyl-phosphate synthase large chain; Belongs to the CarB family. | 0.789 |
H3K5H5_9FIRM | pyrB | GCA_900128435_00056 | GCA_900128435_00615 | Uracil-xanthine permease. | Aspartate carbamoyltransferase; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family. | 0.925 |
H3K5H5_9FIRM | pyrC | GCA_900128435_00056 | GCA_900128435_00614 | Uracil-xanthine permease. | Dihydroorotase; Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate; Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily. | 0.879 |
H3K5H5_9FIRM | pyrD | GCA_900128435_00056 | GCA_900128435_00508 | Uracil-xanthine permease. | Dihydroorotate dehydrogenase; Catalyzes the conversion of dihydroorotate to orotate. | 0.805 |
H3K5H5_9FIRM | pyrE | GCA_900128435_00056 | GCA_900128435_00610 | Uracil-xanthine permease. | Orotate phosphoribosyltransferase; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP). | 0.828 |
H3K5H5_9FIRM | pyrF | GCA_900128435_00056 | GCA_900128435_00611 | Uracil-xanthine permease. | Orotidine 5'-phosphate decarboxylase; Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP); Belongs to the OMP decarboxylase family. Type 1 subfamily. | 0.825 |
H3K5H5_9FIRM | pyrK | GCA_900128435_00056 | GCA_900128435_00509 | Uracil-xanthine permease. | Dihydroorotate dehydrogenase B (NAD(+)), electron transfer subunit; Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD(+). | 0.709 |
H3K5H5_9FIRM | pyrR | GCA_900128435_00056 | GCA_900128435_02017 | Uracil-xanthine permease. | Pyrimidine operon regulatory protein; Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant; Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrR subfamily. | 0.894 |
H3K883_9FIRM | H3K5H5_9FIRM | GCA_900128435_01750 | GCA_900128435_00056 | Uncharacterized protein. | Uracil-xanthine permease. | 0.556 |
carA | H3K5H5_9FIRM | GCA_900128435_00613 | GCA_900128435_00056 | Carbamoyl-phosphate synthase small chain; Belongs to the CarA family. | Uracil-xanthine permease. | 0.803 |
carA | carB | GCA_900128435_00613 | GCA_900128435_00612 | Carbamoyl-phosphate synthase small chain; Belongs to the CarA family. | Carbamoyl-phosphate synthase large chain; Belongs to the CarB family. | 0.999 |
carA | pyrB | GCA_900128435_00613 | GCA_900128435_00615 | Carbamoyl-phosphate synthase small chain; Belongs to the CarA family. | Aspartate carbamoyltransferase; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family. | 0.999 |
carA | pyrC | GCA_900128435_00613 | GCA_900128435_00614 | Carbamoyl-phosphate synthase small chain; Belongs to the CarA family. | Dihydroorotase; Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate; Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily. | 0.997 |
carA | pyrD | GCA_900128435_00613 | GCA_900128435_00508 | Carbamoyl-phosphate synthase small chain; Belongs to the CarA family. | Dihydroorotate dehydrogenase; Catalyzes the conversion of dihydroorotate to orotate. | 0.887 |
carA | pyrE | GCA_900128435_00613 | GCA_900128435_00610 | Carbamoyl-phosphate synthase small chain; Belongs to the CarA family. | Orotate phosphoribosyltransferase; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP). | 0.931 |
carA | pyrF | GCA_900128435_00613 | GCA_900128435_00611 | Carbamoyl-phosphate synthase small chain; Belongs to the CarA family. | Orotidine 5'-phosphate decarboxylase; Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP); Belongs to the OMP decarboxylase family. Type 1 subfamily. | 0.937 |
carA | pyrK | GCA_900128435_00613 | GCA_900128435_00509 | Carbamoyl-phosphate synthase small chain; Belongs to the CarA family. | Dihydroorotate dehydrogenase B (NAD(+)), electron transfer subunit; Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD(+). | 0.824 |
carA | pyrR | GCA_900128435_00613 | GCA_900128435_02017 | Carbamoyl-phosphate synthase small chain; Belongs to the CarA family. | Pyrimidine operon regulatory protein; Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant; Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrR subfamily. | 0.737 |