STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
H3KAM0_9FIRMSuccinate CoA transferase. (499 aa)    
Predicted Functional Partners:
H3KAM2_9FIRM
Methylmalonyl-CoA mutase domain-containing protein.
  
 
 0.955
NifJ
Pyruvate:ferredoxin (Flavodoxin) oxidoreductase.
    
 0.949
sucC
Succinate--CoA ligase [ADP-forming] subunit beta; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.
   
 0.948
H3KAM1_9FIRM
Methylmalonyl-CoA mutase domain-containing protein.
    
 0.943
sucD
Succinate--CoA ligase [ADP-forming] subunit alpha; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.
   
 0.942
ScpA
Methylmalonyl-CoA mutase large subunit.
  
 
 0.934
H3K724_9FIRM
Methylmalonyl-CoA mutase, small subunit.
  
 
 0.934
SdhA
Succinate dehydrogenase or fumarate reductase, flavoprotein subunit.
   
 
 0.919
SdhB
Succinate dehydrogenase and fumarate reductase iron-sulfur protein.
   
 
 0.918
leuA
2-isopropylmalate synthase; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 2 subfamily.
    
 0.909
Your Current Organism:
Megamonas funiformis
NCBI taxonomy Id: 437897
Other names: DSM 19343, JCM 14723, M. funiformis, Megamonas funiformis Sakon et al. 2008, Megamonas sp. Marseille-P3344, YIT 11815
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