node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
FolK | QueD | GCA_900128435_00223 | GCA_900128435_02037 | 7,8-dihydroneopterin aldolase; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin. | 6-carboxy-5,6,7,8-tetrahydropterin synthase. | 0.516 |
FolK | folE2 | GCA_900128435_00223 | GCA_900128435_00250 | 7,8-dihydroneopterin aldolase; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin. | GTP cyclohydrolase FolE2; Converts GTP to 7,8-dihydroneopterin triphosphate. | 0.670 |
H3K494_9FIRM | QueD | GCA_900128435_02036 | GCA_900128435_02037 | Uncharacterized protein. | 6-carboxy-5,6,7,8-tetrahydropterin synthase. | 0.549 |
H3K494_9FIRM | ahcY | GCA_900128435_02036 | GCA_900128435_02040 | Uncharacterized protein. | Adenosylhomocysteinase; May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine. | 0.640 |
H3K494_9FIRM | mtaD | GCA_900128435_02036 | GCA_900128435_02041 | Uncharacterized protein. | 5-methylthioadenosine/S-adenosylhomocysteine deaminase; Catalyzes the deamination of 5-methylthioadenosine and S- adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine. Belongs to the metallo-dependent hydrolases superfamily. MTA/SAH deaminase family. | 0.532 |
H3K494_9FIRM | queE | GCA_900128435_02036 | GCA_900128435_02038 | Uncharacterized protein. | 7-carboxy-7-deazaguanine synthase; Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7- deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds. | 0.520 |
H3K494_9FIRM | surE | GCA_900128435_02036 | GCA_900128435_02039 | Uncharacterized protein. | 5'-nucleotidase SurE; Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family. | 0.497 |
NrdG | QueD | GCA_900128435_01019 | GCA_900128435_02037 | Anaerobic ribonucleoside-triphosphate reductase-activating protein; Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine. | 6-carboxy-5,6,7,8-tetrahydropterin synthase. | 0.533 |
NrdG | queC | GCA_900128435_01019 | GCA_900128435_00251 | Anaerobic ribonucleoside-triphosphate reductase-activating protein; Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine. | 7-cyano-7-deazaguanine synthase; Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)). | 0.558 |
NrdG | queF | GCA_900128435_01019 | GCA_900128435_01371 | Anaerobic ribonucleoside-triphosphate reductase-activating protein; Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine. | NADPH-dependent 7-cyano-7-deazaguanine reductase; Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1). Belongs to the GTP cyclohydrolase I family. QueF type 1 subfamily. | 0.626 |
QueD | FolK | GCA_900128435_02037 | GCA_900128435_00223 | 6-carboxy-5,6,7,8-tetrahydropterin synthase. | 7,8-dihydroneopterin aldolase; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin. | 0.516 |
QueD | H3K494_9FIRM | GCA_900128435_02037 | GCA_900128435_02036 | 6-carboxy-5,6,7,8-tetrahydropterin synthase. | Uncharacterized protein. | 0.549 |
QueD | NrdG | GCA_900128435_02037 | GCA_900128435_01019 | 6-carboxy-5,6,7,8-tetrahydropterin synthase. | Anaerobic ribonucleoside-triphosphate reductase-activating protein; Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine. | 0.533 |
QueD | ahcY | GCA_900128435_02037 | GCA_900128435_02040 | 6-carboxy-5,6,7,8-tetrahydropterin synthase. | Adenosylhomocysteinase; May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine. | 0.765 |
QueD | folE2 | GCA_900128435_02037 | GCA_900128435_00250 | 6-carboxy-5,6,7,8-tetrahydropterin synthase. | GTP cyclohydrolase FolE2; Converts GTP to 7,8-dihydroneopterin triphosphate. | 0.951 |
QueD | mtaD | GCA_900128435_02037 | GCA_900128435_02041 | 6-carboxy-5,6,7,8-tetrahydropterin synthase. | 5-methylthioadenosine/S-adenosylhomocysteine deaminase; Catalyzes the deamination of 5-methylthioadenosine and S- adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine. Belongs to the metallo-dependent hydrolases superfamily. MTA/SAH deaminase family. | 0.689 |
QueD | queC | GCA_900128435_02037 | GCA_900128435_00251 | 6-carboxy-5,6,7,8-tetrahydropterin synthase. | 7-cyano-7-deazaguanine synthase; Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)). | 0.936 |
QueD | queE | GCA_900128435_02037 | GCA_900128435_02038 | 6-carboxy-5,6,7,8-tetrahydropterin synthase. | 7-carboxy-7-deazaguanine synthase; Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7- deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds. | 0.998 |
QueD | queF | GCA_900128435_02037 | GCA_900128435_01371 | 6-carboxy-5,6,7,8-tetrahydropterin synthase. | NADPH-dependent 7-cyano-7-deazaguanine reductase; Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1). Belongs to the GTP cyclohydrolase I family. QueF type 1 subfamily. | 0.803 |
QueD | surE | GCA_900128435_02037 | GCA_900128435_02039 | 6-carboxy-5,6,7,8-tetrahydropterin synthase. | 5'-nucleotidase SurE; Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family. | 0.747 |