STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ku-2ATP-dependent DNA ligase protein Ku; With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD. Belongs to the prokaryotic Ku family. (270 aa)    
Predicted Functional Partners:
AZC_1006
ATP-dependent DNA ligase.
 
  
 0.987
ku
ATP-dependent DNA ligase protein Ku; With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD. Belongs to the prokaryotic Ku family.
 
  
 
0.976
AZC_2284
Topoisomerase IB.
 
    0.650
AZC_0393
Putative ATP dependent DNA ligase.
 
  
 0.584
AZC_1004
Hypothetical protein.
       0.567
AZC_2285
Protein of unknown function; DUF892.
 
    0.551
AZC_0328
Protein of unknown function; DUF72.
 
    0.504
AZC_0250
Protein of unknown function; DUF72.
 
    0.503
AZC_0824
Putative oxidoreductase; Short-chain dehydrogenase reductase (SDR)family.
  
     0.400
Your Current Organism:
Azorhizobium caulinodans
NCBI taxonomy Id: 438753
Other names: A. caulinodans ORS 571, Azorhizobium caulinodans ORS 571, Azorhizobium caulinodans str. ORS 571, Azorhizobium caulinodans strain ORS 571, Rhizobium sp. ORS 571
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