| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| AZC_1700 | AZC_2003 | AZC_1700 | AZC_2003 | Putative membrane-associated zinc metallopeptidase; Peptidase M50. | Peptidase S26A; Belongs to the peptidase S26 family. | 0.818 |
| AZC_1700 | yidC | AZC_1700 | AZC_4053 | Putative membrane-associated zinc metallopeptidase; Peptidase M50. | 60 kDa inner membrane protein; Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins. | 0.537 |
| AZC_2000 | AZC_2003 | AZC_2000 | AZC_2003 | RelA/SpoT protein; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. | Peptidase S26A; Belongs to the peptidase S26 family. | 0.696 |
| AZC_2000 | era | AZC_2000 | AZC_2005 | RelA/SpoT protein; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. | Transcriptional regulator; An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism. | 0.704 |
| AZC_2000 | recO | AZC_2000 | AZC_2006 | RelA/SpoT protein; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. | Recombination protein O; Involved in DNA repair and RecF pathway recombination. | 0.503 |
| AZC_2000 | rnc | AZC_2000 | AZC_2004 | RelA/SpoT protein; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. | Ribonuclease III; Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism. | 0.527 |
| AZC_2000 | rnhB | AZC_2000 | AZC_2398 | RelA/SpoT protein; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. | Ribonuclease H; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids; Belongs to the RNase HII family. | 0.588 |
| AZC_2003 | AZC_1700 | AZC_2003 | AZC_1700 | Peptidase S26A; Belongs to the peptidase S26 family. | Putative membrane-associated zinc metallopeptidase; Peptidase M50. | 0.818 |
| AZC_2003 | AZC_2000 | AZC_2003 | AZC_2000 | Peptidase S26A; Belongs to the peptidase S26 family. | RelA/SpoT protein; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. | 0.696 |
| AZC_2003 | era | AZC_2003 | AZC_2005 | Peptidase S26A; Belongs to the peptidase S26 family. | Transcriptional regulator; An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism. | 0.857 |
| AZC_2003 | lepA | AZC_2003 | AZC_0257 | Peptidase S26A; Belongs to the peptidase S26 family. | GTP-binding LepA protein; Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre- translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP- dependent manner. | 0.782 |
| AZC_2003 | recO | AZC_2003 | AZC_2006 | Peptidase S26A; Belongs to the peptidase S26 family. | Recombination protein O; Involved in DNA repair and RecF pathway recombination. | 0.867 |
| AZC_2003 | rnc | AZC_2003 | AZC_2004 | Peptidase S26A; Belongs to the peptidase S26 family. | Ribonuclease III; Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism. | 0.967 |
| AZC_2003 | rnhB | AZC_2003 | AZC_2398 | Peptidase S26A; Belongs to the peptidase S26 family. | Ribonuclease H; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids; Belongs to the RNase HII family. | 0.734 |
| AZC_2003 | secD | AZC_2003 | AZC_2894 | Peptidase S26A; Belongs to the peptidase S26 family. | SecD export membrane protein; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA. | 0.825 |
| AZC_2003 | secF | AZC_2003 | AZC_2893 | Peptidase S26A; Belongs to the peptidase S26 family. | SecF protein; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA. | 0.784 |
| AZC_2003 | yidC | AZC_2003 | AZC_4053 | Peptidase S26A; Belongs to the peptidase S26 family. | 60 kDa inner membrane protein; Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins. | 0.827 |
| era | AZC_2000 | AZC_2005 | AZC_2000 | Transcriptional regulator; An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism. | RelA/SpoT protein; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. | 0.704 |
| era | AZC_2003 | AZC_2005 | AZC_2003 | Transcriptional regulator; An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism. | Peptidase S26A; Belongs to the peptidase S26 family. | 0.857 |
| era | lepA | AZC_2005 | AZC_0257 | Transcriptional regulator; An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism. | GTP-binding LepA protein; Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre- translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP- dependent manner. | 0.696 |