node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
AZC_1748 | AZC_1998 | AZC_1748 | AZC_1998 | Conserved hypothetical protein; Streptomyces cyclase/dehydrase. | Ubiquinone biosynthesis hydroxylase; UbiH/UbiF/VisC/COQ6. | 0.551 |
AZC_1748 | AZC_3918 | AZC_1748 | AZC_3918 | Conserved hypothetical protein; Streptomyces cyclase/dehydrase. | 2-polyprenylphenol 6-hydroxylase. | 0.499 |
AZC_1748 | AZC_4229 | AZC_1748 | AZC_4229 | Conserved hypothetical protein; Streptomyces cyclase/dehydrase. | Ubiquinone biosynthesis hydroxylase; UbiH/UbiF/VisC/COQ6. | 0.507 |
AZC_1748 | ubiA | AZC_1748 | AZC_2378 | Conserved hypothetical protein; Streptomyces cyclase/dehydrase. | 4-hydroxybenzoate polyprenyl transferase; Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3-octaprenyl-4-hydroxybenzoate. | 0.607 |
AZC_1748 | ubiE-2 | AZC_1748 | AZC_3919 | Conserved hypothetical protein; Streptomyces cyclase/dehydrase. | Ubiquinone/menaquinone biosynthesis methyltransferase; Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3- methyl-6-methoxy-1,4-benzoquinol (DMQH2). | 0.470 |
AZC_1748 | ubiG | AZC_1748 | AZC_4300 | Conserved hypothetical protein; Streptomyces cyclase/dehydrase. | Ubiquinone biosynthesis O-methyltransferase; O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway; Belongs to the methyltransferase superfamily. UbiG/COQ3 family. | 0.705 |
AZC_1998 | AZC_1748 | AZC_1998 | AZC_1748 | Ubiquinone biosynthesis hydroxylase; UbiH/UbiF/VisC/COQ6. | Conserved hypothetical protein; Streptomyces cyclase/dehydrase. | 0.551 |
AZC_1998 | AZC_3918 | AZC_1998 | AZC_3918 | Ubiquinone biosynthesis hydroxylase; UbiH/UbiF/VisC/COQ6. | 2-polyprenylphenol 6-hydroxylase. | 0.614 |
AZC_1998 | AZC_4229 | AZC_1998 | AZC_4229 | Ubiquinone biosynthesis hydroxylase; UbiH/UbiF/VisC/COQ6. | Ubiquinone biosynthesis hydroxylase; UbiH/UbiF/VisC/COQ6. | 0.920 |
AZC_1998 | ubiA | AZC_1998 | AZC_2378 | Ubiquinone biosynthesis hydroxylase; UbiH/UbiF/VisC/COQ6. | 4-hydroxybenzoate polyprenyl transferase; Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3-octaprenyl-4-hydroxybenzoate. | 0.687 |
AZC_1998 | ubiE-2 | AZC_1998 | AZC_3919 | Ubiquinone biosynthesis hydroxylase; UbiH/UbiF/VisC/COQ6. | Ubiquinone/menaquinone biosynthesis methyltransferase; Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3- methyl-6-methoxy-1,4-benzoquinol (DMQH2). | 0.928 |
AZC_1998 | ubiG | AZC_1998 | AZC_4300 | Ubiquinone biosynthesis hydroxylase; UbiH/UbiF/VisC/COQ6. | Ubiquinone biosynthesis O-methyltransferase; O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway; Belongs to the methyltransferase superfamily. UbiG/COQ3 family. | 0.965 |
AZC_3913 | AZC_3918 | AZC_3913 | AZC_3918 | DNA/pantothenate metabolism flavoprotein; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. | 2-polyprenylphenol 6-hydroxylase. | 0.426 |
AZC_3917 | AZC_3918 | AZC_3917 | AZC_3918 | Hypothetical protein. | 2-polyprenylphenol 6-hydroxylase. | 0.723 |
AZC_3917 | AZC_3920 | AZC_3917 | AZC_3920 | Hypothetical protein. | Conserved hypothetical protein; Abortive infection protein. | 0.466 |
AZC_3917 | ubiE-2 | AZC_3917 | AZC_3919 | Hypothetical protein. | Ubiquinone/menaquinone biosynthesis methyltransferase; Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3- methyl-6-methoxy-1,4-benzoquinol (DMQH2). | 0.622 |
AZC_3918 | AZC_1748 | AZC_3918 | AZC_1748 | 2-polyprenylphenol 6-hydroxylase. | Conserved hypothetical protein; Streptomyces cyclase/dehydrase. | 0.499 |
AZC_3918 | AZC_1998 | AZC_3918 | AZC_1998 | 2-polyprenylphenol 6-hydroxylase. | Ubiquinone biosynthesis hydroxylase; UbiH/UbiF/VisC/COQ6. | 0.614 |
AZC_3918 | AZC_3913 | AZC_3918 | AZC_3913 | 2-polyprenylphenol 6-hydroxylase. | DNA/pantothenate metabolism flavoprotein; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. | 0.426 |
AZC_3918 | AZC_3917 | AZC_3918 | AZC_3917 | 2-polyprenylphenol 6-hydroxylase. | Hypothetical protein. | 0.723 |