STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
panBKetopantoate hydroxymethyltransferase precursor; Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha- ketoisovalerate to form ketopantoate; Belongs to the PanB family. (235 aa)    
Predicted Functional Partners:
panC
Pantoate-beta-alanine ligase; Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate. Belongs to the pantothenate synthetase family.
  
 0.998
AZC_0464
Ketopantoate reductase; ApbA/PanE precursor.
    
 0.945
ilvE
Branched-chain amino acid aminotransferase I; Acts on leucine, isoleucine and valine. Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.
    
 0.925
AZC_1408
Dihydroxy-acid dehydratase; Belongs to the IlvD/Edd family.
     
 0.910
ilvD
Dihydroxy-acid dehydratase; Belongs to the IlvD/Edd family.
     
 0.910
AZC_2468
Nicotinate-nucleotide pyrophosphorylase; Belongs to the NadC/ModD family.
     0.695
AZC_4330
Hypothetical protein.
       0.558
AZC_3913
DNA/pantothenate metabolism flavoprotein; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family.
 
   
 0.552
guaA
Putative GMP synthase; Catalyzes the synthesis of GMP from XMP.
     
 0.547
AZC_4332
Conserved hypothetical protein; NnrU.
       0.539
Your Current Organism:
Azorhizobium caulinodans
NCBI taxonomy Id: 438753
Other names: A. caulinodans ORS 571, Azorhizobium caulinodans ORS 571, Azorhizobium caulinodans str. ORS 571, Azorhizobium caulinodans strain ORS 571, Rhizobium sp. ORS 571
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