| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| AZC_0014 | AZC_4340 | AZC_0014 | AZC_4340 | S-adenosylmethionine synthetase; Belongs to the AdoMet synthase family. | 5,10-methylenetetrahydrofolate reductase; Belongs to the methylenetetrahydrofolate reductase family. | 0.811 |
| AZC_0014 | AZC_4341 | AZC_0014 | AZC_4341 | S-adenosylmethionine synthetase; Belongs to the AdoMet synthase family. | 5-methyltetrahydrofolate-homocysteine methyltransferase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | 0.955 |
| AZC_0014 | ahcY | AZC_0014 | AZC_4042 | S-adenosylmethionine synthetase; Belongs to the AdoMet synthase family. | S-adenosyl-L-homocysteine hydrolase; May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine. | 0.850 |
| AZC_0014 | fhs | AZC_0014 | AZC_0897 | S-adenosylmethionine synthetase; Belongs to the AdoMet synthase family. | Formate-tetrahydrofolate ligase; Belongs to the formate--tetrahydrofolate ligase family. | 0.458 |
| AZC_1375 | AZC_1377 | AZC_1375 | AZC_1377 | Aminomethyltransferase; Belongs to the GcvT family. | Aminomethyltransferase; Belongs to the GcvT family. | 0.958 |
| AZC_1375 | AZC_4245 | AZC_1375 | AZC_4245 | Aminomethyltransferase; Belongs to the GcvT family. | Glycine cleavage system T protein. | 0.923 |
| AZC_1375 | AZC_4340 | AZC_1375 | AZC_4340 | Aminomethyltransferase; Belongs to the GcvT family. | 5,10-methylenetetrahydrofolate reductase; Belongs to the methylenetetrahydrofolate reductase family. | 0.918 |
| AZC_1375 | AZC_4341 | AZC_1375 | AZC_4341 | Aminomethyltransferase; Belongs to the GcvT family. | 5-methyltetrahydrofolate-homocysteine methyltransferase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | 0.954 |
| AZC_1375 | fhs | AZC_1375 | AZC_0897 | Aminomethyltransferase; Belongs to the GcvT family. | Formate-tetrahydrofolate ligase; Belongs to the formate--tetrahydrofolate ligase family. | 0.931 |
| AZC_1377 | AZC_1375 | AZC_1377 | AZC_1375 | Aminomethyltransferase; Belongs to the GcvT family. | Aminomethyltransferase; Belongs to the GcvT family. | 0.958 |
| AZC_1377 | AZC_4245 | AZC_1377 | AZC_4245 | Aminomethyltransferase; Belongs to the GcvT family. | Glycine cleavage system T protein. | 0.924 |
| AZC_1377 | AZC_4340 | AZC_1377 | AZC_4340 | Aminomethyltransferase; Belongs to the GcvT family. | 5,10-methylenetetrahydrofolate reductase; Belongs to the methylenetetrahydrofolate reductase family. | 0.915 |
| AZC_1377 | AZC_4341 | AZC_1377 | AZC_4341 | Aminomethyltransferase; Belongs to the GcvT family. | 5-methyltetrahydrofolate-homocysteine methyltransferase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | 0.954 |
| AZC_1377 | fhs | AZC_1377 | AZC_0897 | Aminomethyltransferase; Belongs to the GcvT family. | Formate-tetrahydrofolate ligase; Belongs to the formate--tetrahydrofolate ligase family. | 0.928 |
| AZC_1584 | AZC_2180 | AZC_1584 | AZC_2180 | Cystathionine beta-lyase. | O-acetylhomoserine/O-acetylserine sulfhydrylase. | 0.942 |
| AZC_1584 | AZC_4340 | AZC_1584 | AZC_4340 | Cystathionine beta-lyase. | 5,10-methylenetetrahydrofolate reductase; Belongs to the methylenetetrahydrofolate reductase family. | 0.706 |
| AZC_1584 | AZC_4341 | AZC_1584 | AZC_4341 | Cystathionine beta-lyase. | 5-methyltetrahydrofolate-homocysteine methyltransferase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | 0.978 |
| AZC_1584 | ahcY | AZC_1584 | AZC_4042 | Cystathionine beta-lyase. | S-adenosyl-L-homocysteine hydrolase; May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine. | 0.922 |
| AZC_1584 | metZ | AZC_1584 | AZC_4021 | Cystathionine beta-lyase. | O-succinylhomoserine sulfhydrylase; Catalyzes the formation of L-homocysteine from O-succinyl-L- homoserine (OSHS) and hydrogen sulfide. | 0.923 |
| AZC_2180 | AZC_1584 | AZC_2180 | AZC_1584 | O-acetylhomoserine/O-acetylserine sulfhydrylase. | Cystathionine beta-lyase. | 0.942 |