node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
SDB01595.1 | pth | SAMN02910293_00005 | SAMN02910293_00003 | Hypothetical protein. | peptidyl-tRNA hydrolase, PTH1 family; The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis. Belongs to the PTH family. | 0.444 |
SDB01595.1 | ychF | SAMN02910293_00005 | SAMN02910293_00004 | Hypothetical protein. | Hypothetical protein; ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner. | 0.681 |
SDB04315.1 | guaA | SAMN02910293_00207 | SAMN02910293_01673 | Ribonucleoside-diphosphate reductase class Ib alpha subunit; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. | GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP. | 0.570 |
SDB04315.1 | pyrG | SAMN02910293_00207 | SAMN02910293_00736 | Ribonucleoside-diphosphate reductase class Ib alpha subunit; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. | CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates. | 0.728 |
SDB04315.1 | ychF | SAMN02910293_00207 | SAMN02910293_00004 | Ribonucleoside-diphosphate reductase class Ib alpha subunit; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. | Hypothetical protein; ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner. | 0.668 |
argS | guaA | SAMN02910293_00105 | SAMN02910293_01673 | arginyl-tRNA synthetase. | GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP. | 0.993 |
argS | lepA | SAMN02910293_00105 | SAMN02910293_01487 | arginyl-tRNA synthetase. | GTP-binding protein LepA; Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre- translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP- dependent manner. | 0.558 |
argS | metG | SAMN02910293_00105 | SAMN02910293_00401 | arginyl-tRNA synthetase. | methionyl-tRNA synthetase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation; Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 2B subfamily. | 0.936 |
argS | pheT | SAMN02910293_00105 | SAMN02910293_02177 | arginyl-tRNA synthetase. | phenylalanyl-tRNA synthetase beta subunit; Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily. | 0.788 |
argS | prfA | SAMN02910293_00105 | SAMN02910293_02316 | arginyl-tRNA synthetase. | Bacterial peptide chain release factor 1 (bRF-1); Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA. | 0.582 |
argS | pyrG | SAMN02910293_00105 | SAMN02910293_00736 | arginyl-tRNA synthetase. | CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates. | 0.819 |
argS | ychF | SAMN02910293_00105 | SAMN02910293_00004 | arginyl-tRNA synthetase. | Hypothetical protein; ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner. | 0.675 |
guaA | SDB04315.1 | SAMN02910293_01673 | SAMN02910293_00207 | GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP. | Ribonucleoside-diphosphate reductase class Ib alpha subunit; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. | 0.570 |
guaA | argS | SAMN02910293_01673 | SAMN02910293_00105 | GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP. | arginyl-tRNA synthetase. | 0.993 |
guaA | lepA | SAMN02910293_01673 | SAMN02910293_01487 | GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP. | GTP-binding protein LepA; Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre- translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP- dependent manner. | 0.515 |
guaA | metG | SAMN02910293_01673 | SAMN02910293_00401 | GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP. | methionyl-tRNA synthetase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation; Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 2B subfamily. | 0.739 |
guaA | pheT | SAMN02910293_01673 | SAMN02910293_02177 | GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP. | phenylalanyl-tRNA synthetase beta subunit; Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily. | 0.902 |
guaA | pth | SAMN02910293_01673 | SAMN02910293_00003 | GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP. | peptidyl-tRNA hydrolase, PTH1 family; The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis. Belongs to the PTH family. | 0.543 |
guaA | pyrG | SAMN02910293_01673 | SAMN02910293_00736 | GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP. | CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates. | 0.987 |
guaA | ychF | SAMN02910293_01673 | SAMN02910293_00004 | GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP. | Hypothetical protein; ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner. | 0.690 |