close STRING v12.5 is now available!
The next version of STRING is ready for use in your analyses: updated networks across STRING newly available directed regulatory networks a new typed view showing functional, physical, and regulatory edges in one network new clustering options and cluster-based layouts … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Dalk_1024TIGRFAM: acetyl coenzyme A synthetase (ADP forming), alpha domain protein; PFAM: CoA-binding domain protein; KEGG: mgm:Mmc1_1098 CoA-binding domain protein; IMG reference gene:2503006725; PFAM: CoA binding domain; TIGRFAM: acetyl coenzyme A synthetase (ADP forming), alpha domain. (726 aa)    
Predicted Functional Partners:
Dalk_4144
Pyruvate-ferredoxin oxidoreductase, alpha subunit; PFAM: 4Fe-4S ferredoxin iron-sulfur binding domain protein; pyruvate ferredoxin/flavodoxin oxidoreductase; pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; 4Fe-4S ferredoxin, iron-sulphur binding, conserved site; KEGG: dvl:Dvul_0348 pyruvate flavodoxin/ferredoxin oxidoreductase domain-containing protein; IMG reference gene:2503009890; PFAM: Domain of unknown function; domain; Pyruvate ferredoxin/flavodoxin oxidoreductase; Thiamine pyrophosphate enzyme, C-terminal TPP binding domain; TIGRFAM: pyruvate:ferredoxin (flavodoxin [...]
  
 0.916
Dalk_4382
PFAM: GCN5-related N-acetyltransferase; acetyl-CoA hydrolase/transferase; KEGG: syn:slr1888 hypothetical protein; IMG reference gene:2503010130; PFAM: Acetyl-CoA hydrolase/transferase N-terminal domain; Acetyltransferase (GNAT) family.
   
  0.895
Dalk_3640
Acetyl-CoA synthetase (Acetate-CoA ligase); PFAM: AMP-dependent synthetase and ligase; KEGG: dol:Dole_1499 AMP-dependent synthetase and ligase; IMG reference gene:2503009384; PFAM: Domain of unknown function (DUF3448); AMP-binding enzyme.
    
 0.833
Dalk_3784
TIGRFAM: succinyl-CoA synthetase, alpha subunit; PFAM: CoA-binding domain protein; ATP-citrate lyase/succinyl-CoA ligase; KEGG: dol:Dole_0073 succinyl-CoA synthetase, alpha subunit; IMG reference gene:2503009528; PFAM: CoA binding domain; CoA-ligase; TIGRFAM: succinyl-CoA synthetase, alpha subunit.
    
0.833
Dalk_0307
KEGG: dol:Dole_0137 ATP-grasp domain-containing protein; IMG reference gene:2503006004; PFAM: ATP-grasp domain.
  
  
 
0.832
Dalk_2329
Acetyl-CoA synthetase (Acetate-CoA ligase); TIGRFAM: acetate/CoA ligase; PFAM: AMP-dependent synthetase and ligase; KEGG: sfu:Sfum_0745 acetate--CoA ligase; IMG reference gene:2503008049; PFAM: Domain of unknown function (DUF3448); AMP-binding enzyme; TIGRFAM: acetate--CoA ligase.
    
 0.832
Dalk_3783
Succinate-CoA ligase (ADP-forming), beta subunit; KEGG: dol:Dole_0074 succinyl-CoA synthetase, beta subunit; TIGRFAM: succinyl-CoA synthetase, beta subunit; PFAM: ATP-citrate lyase/succinyl-CoA ligase; ATP-grasp domain protein; IMG reference gene:2503009527; PFAM: CoA-ligase; ATP-grasp domain; TIGRFAM: succinyl-CoA synthetase, beta subunit.
    
  0.826
Dalk_3660
KEGG: dol:Dole_0156 acetyl-CoA acetyltransferase; TIGRFAM: acetyl-CoA acetyltransferase; PFAM: Thiolase; IMG reference gene:2503009404; PFAM: Thiolase, C-terminal domain; Thiolase, N-terminal domain; TIGRFAM: acetyl-CoA acetyltransferases.
  
 
  0.824
Dalk_3863
KEGG: dol:Dole_2187 acetyl-CoA acetyltransferase; TIGRFAM: acetyl-CoA acetyltransferase; PFAM: Thiolase; IMG reference gene:2503009607; PFAM: Thiolase, C-terminal domain; Thiolase, N-terminal domain; TIGRFAM: acetyl-CoA acetyltransferases.
  
 
  0.821
Dalk_3782
Pyruvate carboxylase; PFAM: biotin/lipoyl attachment domain-containing protein; pyruvate carboxyltransferase; Conserved carboxylase region; KEGG: dol:Dole_0075 hypothetical protein; IMG reference gene:2503009526; PFAM: HMGL-like; Conserved carboxylase domain; Biotin-requiring enzyme.
    
 0.817
Your Current Organism:
Desulfatibacillum alkenivorans AK01
NCBI taxonomy Id: 439235
Other names: D. alkenivorans AK-01, Desulfatibacillum alkenivorans AK-01, Desulfatibacillum alkenivorans str. AK-01, Desulfatibacillum alkenivorans strain AK-01
Server load: low (20%) [HD]