STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Dalk_3377KEGG: dol:Dole_2816 4-diphosphocytidyl-2C-methyl-D-erythritol kinase; TIGRFAM: 4-diphosphocytidyl-2C-methyl-D-erythritol kinase; PFAM: GHMP kinase; GHMP kinase domain protein; IMG reference gene:2503009108; PFAM: GHMP kinases C terminal; GHMP kinases N terminal domain; TIGRFAM: 4-diphosphocytidyl-2C-methyl-D-erythritol kinase. (284 aa)    
Predicted Functional Partners:
Dalk_0768
KEGG: dol:Dole_1666 2C-methyl-D-erythritol 2,4-cyclodiphosphate synthase; TIGRFAM: 2C-methyl-D-erythritol 2,4-cyclodiphosphate synthase; PFAM: MECDP-synthase; IMG reference gene:2503006469; PFAM: YgbB family; TIGRFAM: 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase.
 
 
 0.972
Dalk_4391
TIGRFAM: 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase; PFAM: 4-diphosphocytidyl-2C-methyl-D-erythritol synthase; KEGG: cth:Cthe_2941 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase; IMG reference gene:2503010139; PFAM: Uncharacterized protein family UPF0007; TIGRFAM: 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase.
 
  
 0.971
Dalk_3122
TIGRFAM: dimethyladenosine transferase; PFAM: ribosomal RNA adenine methylase transferase; KEGG: dol:Dole_1636 dimethyladenosine transferase; IMG reference gene:2503008851; PFAM: Ribosomal RNA adenine dimethylase; TIGRFAM: dimethyladenosine transferase.
  
 0.913
Dalk_3710
KEGG: dol:Dole_0383 hydroxymethylbutenyl pyrophosphate reductase; TIGRFAM: hydroxymethylbutenyl pyrophosphate reductase; PFAM: LytB protein; IMG reference gene:2503009454; PFAM: LytB protein; UbiA prenyltransferase family; TIGRFAM: (E)-4-hydroxy-3-methyl-but-2-enyl pyrophosphate reductase (IPP and DMAPP forming).
 
   
 0.859
Dalk_3159
Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate; IMG reference gene:2503008888; PFAM: 1-deoxy-D-xylulose 5-phosphate reductoisomerase; 1-deoxy-D-xylulose 5-phosphate reductoisomerase C-terminal; TIGRFAM: 1-deoxy-D-xylulose 5-phosphate reductoisomerase.
 
   
 0.829
Dalk_3378
PFAM: Domain of unknown function DUF1844; KEGG: sfu:Sfum_3650 conserved hypothetical cytosolic protein; IMG reference gene:2503009109; PFAM: Domain of unknown function (DUF1844).
       0.828
Dalk_5105
KEGG: ppd:Ppro_1751 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate synthase; TIGRFAM: 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate synthase; PFAM: IspG family protein; IMG reference gene:2503010864; PFAM: GcpE protein; TIGRFAM: 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate synthase.
 
   
 0.807
Dalk_3379
D-3-phosphoglycerate dehydrogenase; Catalyzes the formation of 3-phosphonooxypyruvate from 3-phospho-D-glycerate in serine biosynthesis; can also reduce alpha ketoglutarate to form 2-hydroxyglutarate; IMG reference gene:2503009110; PFAM: D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain; ACT domain; D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain; TIGRFAM: D-3-phosphoglycerate dehydrogenase.
       0.738
Dalk_0836
TIGRFAM: deoxyxylulose-5-phosphate synthase; PFAM: Transketolase central region; Transketolase domain protein; KEGG: dol:Dole_1662 deoxyxylulose-5-phosphate synthase; IMG reference gene:2503006537; PFAM: Transketolase, C-terminal domain; Transketolase, pyrimidine binding domain; TIGRFAM: 1-deoxy-D-xylulose-5-phosphate synthase.
 
   
 0.684
Dalk_4646
KEGG: dol:Dole_2306 tRNA (guanine-N1)-methyltransferase; TIGRFAM: tRNA (guanine-N1)-methyltransferase; PFAM: tRNA (guanine-N1-)-methyltransferase; IMG reference gene:2503010402; PFAM: tRNA (Guanine-1)-methyltransferase; TIGRFAM: tRNA (guanine-N1)-methyltransferase.
  
 
 0.645
Your Current Organism:
Desulfatibacillum alkenivorans AK01
NCBI taxonomy Id: 439235
Other names: D. alkenivorans AK-01, Desulfatibacillum alkenivorans AK-01, Desulfatibacillum alkenivorans str. AK-01, Desulfatibacillum alkenivorans strain AK-01
Server load: low (22%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.