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STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Dalk_3379D-3-phosphoglycerate dehydrogenase; Catalyzes the formation of 3-phosphonooxypyruvate from 3-phospho-D-glycerate in serine biosynthesis; can also reduce alpha ketoglutarate to form 2-hydroxyglutarate; IMG reference gene:2503009110; PFAM: D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain; ACT domain; D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain; TIGRFAM: D-3-phosphoglycerate dehydrogenase. (526 aa)    
Predicted Functional Partners:
Dalk_3380
Phosphoserine aminotransferase; Catalyzes the formation of 3-phosphonooxypyruvate and glutamate from O-phospho-L-serine and 2-oxoglutarate; required both in major phosphorylated pathway of serine biosynthesis and in the biosynthesis of pyridoxine; IMG reference gene:2503009111; PFAM: Aminotransferase class-V; TIGRFAM: phosphoserine aminotransferase.
 
 0.995
Dalk_2091
PFAM: amine oxidase; FAD dependent oxidoreductase; KEGG: dol:Dole_0266 amine oxidase; IMG reference gene:2503007810; PFAM: Flavin containing amine oxidoreductase.
    
 0.885
Dalk_4144
Pyruvate-ferredoxin oxidoreductase, alpha subunit; PFAM: 4Fe-4S ferredoxin iron-sulfur binding domain protein; pyruvate ferredoxin/flavodoxin oxidoreductase; pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; 4Fe-4S ferredoxin, iron-sulphur binding, conserved site; KEGG: dvl:Dvul_0348 pyruvate flavodoxin/ferredoxin oxidoreductase domain-containing protein; IMG reference gene:2503009890; PFAM: Domain of unknown function; domain; Pyruvate ferredoxin/flavodoxin oxidoreductase; Thiamine pyrophosphate enzyme, C-terminal TPP binding domain; TIGRFAM: pyruvate:ferredoxin (flavodoxin [...]
  
 
 0.884
Dalk_1714
Phosphoglycerate mutase (GpmB protein); Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate; IMG reference gene:2503007424; PFAM: Metalloenzyme superfamily; BPG-independent PGAM N-terminus (iPGM_N); TIGRFAM: 2,3-bisphosphoglycerate-independent phosphoglycerate mutase.
    
 0.839
Dalk_1700
KEGG: dol:Dole_1013 sulfate adenylyltransferase; TIGRFAM: sulfate adenylyltransferase; PFAM: ATP-sulfurylase; adenylylsulfate kinase; IMG reference gene:2503007410; PFAM: ATP-sulfurylase; Adenylylsulphate kinase; TIGRFAM: adenylylsulfate kinase (apsK); ATP sulphurylase.
   
  
 0.814
Dalk_1900
TIGRFAM: ribosomal protein L6 signature 1; PFAM: ribosomal protein L6; KEGG: dol:Dole_0723 ribosomal protein L6; IMG reference gene:2503007612; PFAM: Ribosomal protein L6; TIGRFAM: ribosomal protein L6, bacterial type.
   
   0.813
Dalk_3060
KEGG: sat:SYN_00621 phosphoglycerate mutase; TIGRFAM: phosphonopyruvate decarboxylase-related protein; PFAM: metalloenzyme domain protein; IMG reference gene:2503008787; PFAM: Metalloenzyme superfamily; 2,3-bisphosphoglycerate-independent phosphoglycerate mutase; TIGRFAM: 2,3-bisphosphoglycerate-independent phosphoglycerate mutase, archaeal form.
    
 0.799
Dalk_3029
KEGG: gur:Gura_0598 non-specific serine/threonine protein kinase; PFAM: SNF2-related protein; helicase domain protein; SMART: DEAD-like helicases; IMG reference gene:2503008756; PFAM: SNF2 Helicase protein; Helicase conserved C-terminal domain; SNF2 family N-terminal domain.
   
 0.788
Dalk_1355
KEGG: chy:CHY_0280 glyceraldehyde-3-phosphate dehydrogenase, type I; TIGRFAM: glyceraldehyde-3-phosphate dehydrogenase, type I; PFAM: glyceraldehyde 3-phosphate dehydrogenase; IMG reference gene:2503007060; PFAM: Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain; Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain; TIGRFAM: glyceraldehyde-3-phosphate dehydrogenase, type I.
    
 0.785
Dalk_2862
Putative sirtuin-type regulators for CoA ligase (histone deacetylase superfamily); PFAM: histone deacetylase superfamily; KEGG: HDA2; HDA2 (histone deacetylase 2); histone deacetylase; IMG reference gene:2503008587; PFAM: Histone deacetylase domain.
   
 0.778
Your Current Organism:
Desulfatibacillum alkenivorans AK01
NCBI taxonomy Id: 439235
Other names: D. alkenivorans AK-01, Desulfatibacillum alkenivorans AK-01, Desulfatibacillum alkenivorans str. AK-01, Desulfatibacillum alkenivorans strain AK-01
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