node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
SHG47747.1 | SHG83446.1 | SAMN05443636_0375 | SAMN05443636_1229 | acyl-CoA thioester hydrolase. | 1,4-dihydroxy-2-naphthoate octaprenyltransferase. | 0.425 |
SHG47747.1 | menA | SAMN05443636_0375 | SAMN05443636_2152 | acyl-CoA thioester hydrolase. | 1,4-dihydroxy-2-naphthoate prenyltransferase; Conversion of 1,4-dihydroxy-2-naphthoate (DHNA) to demethylmenaquinone (DMK); Belongs to the MenA family. Type 1 subfamily. | 0.425 |
SHG47747.1 | menB | SAMN05443636_0375 | SAMN05443636_2150 | acyl-CoA thioester hydrolase. | 1,4-Dihydroxy-2-naphthoyl-CoA synthase; Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4-dihydroxy-2- naphthoyl-CoA (DHNA-CoA); Belongs to the enoyl-CoA hydratase/isomerase family. MenB subfamily. | 0.594 |
SHG83446.1 | SHG47747.1 | SAMN05443636_1229 | SAMN05443636_0375 | 1,4-dihydroxy-2-naphthoate octaprenyltransferase. | acyl-CoA thioester hydrolase. | 0.425 |
SHG83446.1 | SHH52420.1 | SAMN05443636_1229 | SAMN05443636_2785 | 1,4-dihydroxy-2-naphthoate octaprenyltransferase. | 3-hydroxy-3-methylglutaryl-coenzyme A reductase; Belongs to the HMG-CoA reductase family. | 0.661 |
SHG83446.1 | SHH57175.1 | SAMN05443636_1229 | SAMN05443636_2890 | 1,4-dihydroxy-2-naphthoate octaprenyltransferase. | Demethylmenaquinone methyltransferase / 2-methoxy-6-polyprenyl-1,4-benzoquinol methylase. | 0.699 |
SHG83446.1 | menA | SAMN05443636_1229 | SAMN05443636_2152 | 1,4-dihydroxy-2-naphthoate octaprenyltransferase. | 1,4-dihydroxy-2-naphthoate prenyltransferase; Conversion of 1,4-dihydroxy-2-naphthoate (DHNA) to demethylmenaquinone (DMK); Belongs to the MenA family. Type 1 subfamily. | 0.780 |
SHH24281.1 | menA | SAMN05443636_2151 | SAMN05443636_2152 | Alkylhydroperoxidase AhpD family core domain-containing protein. | 1,4-dihydroxy-2-naphthoate prenyltransferase; Conversion of 1,4-dihydroxy-2-naphthoate (DHNA) to demethylmenaquinone (DMK); Belongs to the MenA family. Type 1 subfamily. | 0.547 |
SHH24281.1 | menC | SAMN05443636_2151 | SAMN05443636_2153 | Alkylhydroperoxidase AhpD family core domain-containing protein. | O-succinylbenzoate synthase; Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB). | 0.547 |
SHH38526.1 | SHH52420.1 | SAMN05443636_2484 | SAMN05443636_2785 | Farnesyl-diphosphate synthase; Belongs to the FPP/GGPP synthase family. | 3-hydroxy-3-methylglutaryl-coenzyme A reductase; Belongs to the HMG-CoA reductase family. | 0.541 |
SHH38526.1 | menA | SAMN05443636_2484 | SAMN05443636_2152 | Farnesyl-diphosphate synthase; Belongs to the FPP/GGPP synthase family. | 1,4-dihydroxy-2-naphthoate prenyltransferase; Conversion of 1,4-dihydroxy-2-naphthoate (DHNA) to demethylmenaquinone (DMK); Belongs to the MenA family. Type 1 subfamily. | 0.607 |
SHH52420.1 | SHG83446.1 | SAMN05443636_2785 | SAMN05443636_1229 | 3-hydroxy-3-methylglutaryl-coenzyme A reductase; Belongs to the HMG-CoA reductase family. | 1,4-dihydroxy-2-naphthoate octaprenyltransferase. | 0.661 |
SHH52420.1 | SHH38526.1 | SAMN05443636_2785 | SAMN05443636_2484 | 3-hydroxy-3-methylglutaryl-coenzyme A reductase; Belongs to the HMG-CoA reductase family. | Farnesyl-diphosphate synthase; Belongs to the FPP/GGPP synthase family. | 0.541 |
SHH52420.1 | menA | SAMN05443636_2785 | SAMN05443636_2152 | 3-hydroxy-3-methylglutaryl-coenzyme A reductase; Belongs to the HMG-CoA reductase family. | 1,4-dihydroxy-2-naphthoate prenyltransferase; Conversion of 1,4-dihydroxy-2-naphthoate (DHNA) to demethylmenaquinone (DMK); Belongs to the MenA family. Type 1 subfamily. | 0.661 |
SHH57175.1 | SHG83446.1 | SAMN05443636_2890 | SAMN05443636_1229 | Demethylmenaquinone methyltransferase / 2-methoxy-6-polyprenyl-1,4-benzoquinol methylase. | 1,4-dihydroxy-2-naphthoate octaprenyltransferase. | 0.699 |
SHH57175.1 | menA | SAMN05443636_2890 | SAMN05443636_2152 | Demethylmenaquinone methyltransferase / 2-methoxy-6-polyprenyl-1,4-benzoquinol methylase. | 1,4-dihydroxy-2-naphthoate prenyltransferase; Conversion of 1,4-dihydroxy-2-naphthoate (DHNA) to demethylmenaquinone (DMK); Belongs to the MenA family. Type 1 subfamily. | 0.862 |
SHH59936.1 | menA | SAMN05443636_2949 | SAMN05443636_2152 | Isochorismate synthase. | 1,4-dihydroxy-2-naphthoate prenyltransferase; Conversion of 1,4-dihydroxy-2-naphthoate (DHNA) to demethylmenaquinone (DMK); Belongs to the MenA family. Type 1 subfamily. | 0.655 |
SHH59936.1 | menB | SAMN05443636_2949 | SAMN05443636_2150 | Isochorismate synthase. | 1,4-Dihydroxy-2-naphthoyl-CoA synthase; Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4-dihydroxy-2- naphthoyl-CoA (DHNA-CoA); Belongs to the enoyl-CoA hydratase/isomerase family. MenB subfamily. | 0.833 |
SHH59936.1 | menC | SAMN05443636_2949 | SAMN05443636_2153 | Isochorismate synthase. | O-succinylbenzoate synthase; Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB). | 0.547 |
SHH59936.1 | menD | SAMN05443636_2949 | SAMN05443636_2148 | Isochorismate synthase. | 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate synthase; Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2- succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC). | 0.998 |