node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
SHG68512.1 | SHH25391.1 | SAMN05443636_0773 | SAMN05443636_2187 | dITPase. | Transcriptional regulator, XRE family. | 0.710 |
SHG68512.1 | guaAB | SAMN05443636_0773 | SAMN05443636_1117 | dITPase. | GMP synthase (glutamine-hydrolysing); Catalyzes the synthesis of GMP from XMP. | 0.962 |
SHG68512.1 | guaB | SAMN05443636_0773 | SAMN05443636_2029 | dITPase. | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | 0.953 |
SHG68512.1 | purA | SAMN05443636_0773 | SAMN05443636_1226 | dITPase. | Adenylosuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family. | 0.792 |
SHH11921.1 | SHH25391.1 | SAMN05443636_1848 | SAMN05443636_2187 | Phosphoserine phosphatase. | Transcriptional regulator, XRE family. | 0.617 |
SHH11921.1 | SHH36141.1 | SAMN05443636_1848 | SAMN05443636_2414 | Phosphoserine phosphatase. | Cystathionine beta-lyase/cystathionine gamma-synthase. | 0.700 |
SHH11921.1 | SHH37060.1 | SAMN05443636_1848 | SAMN05443636_2440 | Phosphoserine phosphatase. | Phosphatidylserine/phosphatidylglycerophosphate/ cardiolipin synthase. | 0.600 |
SHH11921.1 | glyA | SAMN05443636_1848 | SAMN05443636_2450 | Phosphoserine phosphatase. | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. Also exhibits THF-independent aldolase activity toward beta- hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.935 |
SHH25361.1 | SHH25391.1 | SAMN05443636_2186 | SAMN05443636_2187 | Hypothetical protein; Belongs to the UPF0212 family. | Transcriptional regulator, XRE family. | 0.739 |
SHH25391.1 | SHG68512.1 | SAMN05443636_2187 | SAMN05443636_0773 | Transcriptional regulator, XRE family. | dITPase. | 0.710 |
SHH25391.1 | SHH11921.1 | SAMN05443636_2187 | SAMN05443636_1848 | Transcriptional regulator, XRE family. | Phosphoserine phosphatase. | 0.617 |
SHH25391.1 | SHH25361.1 | SAMN05443636_2187 | SAMN05443636_2186 | Transcriptional regulator, XRE family. | Hypothetical protein; Belongs to the UPF0212 family. | 0.739 |
SHH25391.1 | SHH36141.1 | SAMN05443636_2187 | SAMN05443636_2414 | Transcriptional regulator, XRE family. | Cystathionine beta-lyase/cystathionine gamma-synthase. | 0.869 |
SHH25391.1 | SHH37060.1 | SAMN05443636_2187 | SAMN05443636_2440 | Transcriptional regulator, XRE family. | Phosphatidylserine/phosphatidylglycerophosphate/ cardiolipin synthase. | 0.648 |
SHH25391.1 | ahcY | SAMN05443636_2187 | SAMN05443636_1737 | Transcriptional regulator, XRE family. | Adenosylhomocysteinase; May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine. | 0.648 |
SHH25391.1 | glyA | SAMN05443636_2187 | SAMN05443636_2450 | Transcriptional regulator, XRE family. | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. Also exhibits THF-independent aldolase activity toward beta- hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.688 |
SHH25391.1 | guaAB | SAMN05443636_2187 | SAMN05443636_1117 | Transcriptional regulator, XRE family. | GMP synthase (glutamine-hydrolysing); Catalyzes the synthesis of GMP from XMP. | 0.639 |
SHH25391.1 | guaB | SAMN05443636_2187 | SAMN05443636_2029 | Transcriptional regulator, XRE family. | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | 0.681 |
SHH25391.1 | purA | SAMN05443636_2187 | SAMN05443636_1226 | Transcriptional regulator, XRE family. | Adenylosuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family. | 0.598 |
SHH36141.1 | SHH11921.1 | SAMN05443636_2414 | SAMN05443636_1848 | Cystathionine beta-lyase/cystathionine gamma-synthase. | Phosphoserine phosphatase. | 0.700 |