STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Bsel_0763KEGG: sde:Sde_1829 methionine sulfoxide reductase A. (296 aa)    
Predicted Functional Partners:
uvrB
Excinuclease ABC, B subunit; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate [...]
  
 
 0.882
Bsel_0740
KEGG: geo:Geob_0379 UvrD/REP helicase; TIGRFAM: ATP-dependent DNA helicase PcrA; PFAM: UvrD/REP helicase.
  
  
 0.580
Bsel_0761
SMART: DEAD-like helicase; KEGG: fph:Fphi_1827 DEAD/DEAH box helicase-like protein.
     
 0.523
ribBA
3,4-dihydroxy-2-butanone 4-phosphate synthase; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; In the C-terminal section; belongs to the GTP cyclohydrolase II family.
     
 0.500
Bsel_2461
KEGG: mxa:MXAN_4688 single-stranded-DNA-specific exonuclease RecJ; TIGRFAM: single-stranded-DNA-specific exonuclease RecJ; PFAM: phosphoesterase RecJ domain protein; Single-stranded-DNA-specific exonuclease RecJ-like; phosphoesterase DHHA1.
     
 0.500
dinG
DnaQ family exonuclease/DinG family helicase; 3'-5' exonuclease.
     
 0.499
Bsel_0762
PFAM: Putative helicase A859L; KEGG: dat:HRM2_20610 hypothetical protein.
       0.497
Bsel_0626
DNA-(apurinic or apyrimidinic site) lyase; KEGG: spe:Spro_1261 endonuclease VIII; PFAM: DNA glycosylase/AP lyase, H2TH DNA-binding; Formamidopyrimidine-DNA glycosylase catalytic domain protein; Belongs to the FPG family.
  
  
 0.478
mutM
formamidopyrimidine-DNA glycosylase; Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.
  
  
 0.478
polA
DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.
     
 0.474
Your Current Organism:
Bacillus selenitireducens
NCBI taxonomy Id: 439292
Other names: Bacillus selenitireducens MLS10, [. selenitireducens MLS10, [Bacillus] selenitireducens MLS10
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.