STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
pdhAPyruvate dehydrogenase (acetyl-transferring) E1 component, alpha subunit; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3). (362 aa)    
Predicted Functional Partners:
Bsel_1603
PFAM: Transketolase central region; Transketolase domain protein; KEGG: gem:GM21_0476 transketolase central region.
 0.999
Bsel_1604
PFAM: catalytic domain of components of various dehydrogenase complexes; biotin/lipoyl attachment domain-containing protein; E3 binding domain protein; KEGG: bba:Bd0779 pyruvate dehydrogenase E2.
 
 0.996
Bsel_0601
PFAM: Transketolase central region; Transketolase domain protein; KEGG: rhi:NGR_b19890 acetoin:2,6-dichlorophenolindophenol oxidoreductase beta subunit.
 0.995
Bsel_2252
PFAM: Transketolase central region; Transketolase domain protein; KEGG: ade:Adeh_1826 branched-chain alpha-keto acid dehydrogenase E1 component.
 0.995
Bsel_1605
KEGG: bba:Bd0778 dihydrolipoamide dehydrogenase, E3 subunit; TIGRFAM: dihydrolipoamide dehydrogenase; PFAM: pyridine nucleotide-disulphide oxidoreductase dimerisation region; FAD-dependent pyridine nucleotide-disulphide oxidoreductase.
 
 
 0.993
Bsel_0600
PFAM: catalytic domain of components of various dehydrogenase complexes; biotin/lipoyl attachment domain-containing protein; E3 binding domain protein; KEGG: dat:HRM2_47640 PdhC.
 
 0.991
Bsel_2254
KEGG: pla:Plav_3138 dihydrolipoamide dehydrogenase; TIGRFAM: dihydrolipoamide dehydrogenase; PFAM: pyridine nucleotide-disulphide oxidoreductase dimerisation region; FAD-dependent pyridine nucleotide-disulphide oxidoreductase; glucose-inhibited division protein A.
 
 
 0.972
Bsel_1350
KEGG: dps:DP3116 pyruvate kinase; TIGRFAM: pyruvate kinase; PFAM: Pyruvate kinase barrel; PEP-utilising protein mobile region; Pyruvate kinase alpha/beta; Belongs to the pyruvate kinase family.
  
 
 0.942
Bsel_2251
PFAM: catalytic domain of components of various dehydrogenase complexes; biotin/lipoyl attachment domain-containing protein; E3 binding domain protein; KEGG: pla:Plav_1455 2-oxoglutarate dehydrogenase, E2 subunit, dihydrolipoamide succinyltransferase.
 
 0.925
Bsel_1991
TIGRFAM: formate acetyltransferase; KEGG: dar:Daro_2096 formate acetyltransferase; PFAM: pyruvate formate-lyase PFL; formate C-acetyltransferase glycine radical.
   
 
 0.921
Your Current Organism:
Bacillus selenitireducens
NCBI taxonomy Id: 439292
Other names: Bacillus selenitireducens MLS10, [. selenitireducens MLS10, [Bacillus] selenitireducens MLS10
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