| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| Bsel_0486 | Bsel_1422 | Bsel_0486 | Bsel_1422 | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | Uroporphyrinogen III synthase HEM4; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III. | 0.509 |
| Bsel_0486 | Bsel_1978 | Bsel_0486 | Bsel_1978 | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | PFAM: iron-containing alcohol dehydrogenase; KEGG: asu:Asuc_0591 bifunctional acetaldehyde-CoA/alcohol dehydrogenase; In the C-terminal section; belongs to the iron-containing alcohol dehydrogenase family. | 0.486 |
| Bsel_0486 | Bsel_2172 | Bsel_0486 | Bsel_2172 | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | KEGG: mei:Msip34_2147 ATP/cobalamin adenosyltransferase; TIGRFAM: ATP/cobalamin adenosyltransferase; PFAM: cobalamin adenosyltransferase; Belongs to the Cob(I)alamin adenosyltransferase family. | 0.658 |
| Bsel_0486 | Bsel_2245 | Bsel_0486 | Bsel_2245 | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | methylmalonyl-CoA epimerase; KEGG: scl:sce1655 putative isobutyryl-CoA mutase, chain B; TIGRFAM: methylmalonyl-CoA epimerase; PFAM: cobalamin B12-binding domain protein; Glyoxalase/bleomycin resistance protein/dioxygenase. | 0.518 |
| Bsel_0486 | Bsel_2246 | Bsel_0486 | Bsel_2246 | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | TIGRFAM: methylmalonyl-CoA mutase, large subunit; KEGG: gme:Gmet_3251 methylmalonyl-CoA mutase; PFAM: methylmalonyl-CoA mutase. | 0.519 |
| Bsel_0486 | Bsel_3187 | Bsel_0486 | Bsel_3187 | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | KEGG: sfu:Sfum_0456 LAO/AO transport system ATPase; TIGRFAM: LAO/AO transport system ATPase; PFAM: ArgK protein. | 0.422 |
| Bsel_0486 | icmF | Bsel_0486 | Bsel_3186 | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | methylmalonyl-CoA mutase, large subunit; Catalyzes the reversible interconversion of isobutyryl-CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly. | 0.498 |
| Bsel_1422 | Bsel_0486 | Bsel_1422 | Bsel_0486 | Uroporphyrinogen III synthase HEM4; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III. | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | 0.509 |
| Bsel_1422 | Bsel_2172 | Bsel_1422 | Bsel_2172 | Uroporphyrinogen III synthase HEM4; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III. | KEGG: mei:Msip34_2147 ATP/cobalamin adenosyltransferase; TIGRFAM: ATP/cobalamin adenosyltransferase; PFAM: cobalamin adenosyltransferase; Belongs to the Cob(I)alamin adenosyltransferase family. | 0.587 |
| Bsel_1422 | icmF | Bsel_1422 | Bsel_3186 | Uroporphyrinogen III synthase HEM4; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III. | methylmalonyl-CoA mutase, large subunit; Catalyzes the reversible interconversion of isobutyryl-CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly. | 0.500 |
| Bsel_1978 | Bsel_0486 | Bsel_1978 | Bsel_0486 | PFAM: iron-containing alcohol dehydrogenase; KEGG: asu:Asuc_0591 bifunctional acetaldehyde-CoA/alcohol dehydrogenase; In the C-terminal section; belongs to the iron-containing alcohol dehydrogenase family. | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | 0.486 |
| Bsel_1978 | Bsel_2172 | Bsel_1978 | Bsel_2172 | PFAM: iron-containing alcohol dehydrogenase; KEGG: asu:Asuc_0591 bifunctional acetaldehyde-CoA/alcohol dehydrogenase; In the C-terminal section; belongs to the iron-containing alcohol dehydrogenase family. | KEGG: mei:Msip34_2147 ATP/cobalamin adenosyltransferase; TIGRFAM: ATP/cobalamin adenosyltransferase; PFAM: cobalamin adenosyltransferase; Belongs to the Cob(I)alamin adenosyltransferase family. | 0.477 |
| Bsel_1978 | Bsel_2245 | Bsel_1978 | Bsel_2245 | PFAM: iron-containing alcohol dehydrogenase; KEGG: asu:Asuc_0591 bifunctional acetaldehyde-CoA/alcohol dehydrogenase; In the C-terminal section; belongs to the iron-containing alcohol dehydrogenase family. | methylmalonyl-CoA epimerase; KEGG: scl:sce1655 putative isobutyryl-CoA mutase, chain B; TIGRFAM: methylmalonyl-CoA epimerase; PFAM: cobalamin B12-binding domain protein; Glyoxalase/bleomycin resistance protein/dioxygenase. | 0.525 |
| Bsel_1978 | Bsel_3111 | Bsel_1978 | Bsel_3111 | PFAM: iron-containing alcohol dehydrogenase; KEGG: asu:Asuc_0591 bifunctional acetaldehyde-CoA/alcohol dehydrogenase; In the C-terminal section; belongs to the iron-containing alcohol dehydrogenase family. | Propanediol utilization protein; Involved in 1,2-propanediol (1,2-PD) degradation by catalyzing the conversion of propanoyl-CoA to propanoyl-phosphate. | 0.534 |
| Bsel_1978 | icmF | Bsel_1978 | Bsel_3186 | PFAM: iron-containing alcohol dehydrogenase; KEGG: asu:Asuc_0591 bifunctional acetaldehyde-CoA/alcohol dehydrogenase; In the C-terminal section; belongs to the iron-containing alcohol dehydrogenase family. | methylmalonyl-CoA mutase, large subunit; Catalyzes the reversible interconversion of isobutyryl-CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly. | 0.422 |
| Bsel_2172 | Bsel_0486 | Bsel_2172 | Bsel_0486 | KEGG: mei:Msip34_2147 ATP/cobalamin adenosyltransferase; TIGRFAM: ATP/cobalamin adenosyltransferase; PFAM: cobalamin adenosyltransferase; Belongs to the Cob(I)alamin adenosyltransferase family. | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | 0.658 |
| Bsel_2172 | Bsel_1422 | Bsel_2172 | Bsel_1422 | KEGG: mei:Msip34_2147 ATP/cobalamin adenosyltransferase; TIGRFAM: ATP/cobalamin adenosyltransferase; PFAM: cobalamin adenosyltransferase; Belongs to the Cob(I)alamin adenosyltransferase family. | Uroporphyrinogen III synthase HEM4; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III. | 0.587 |
| Bsel_2172 | Bsel_1978 | Bsel_2172 | Bsel_1978 | KEGG: mei:Msip34_2147 ATP/cobalamin adenosyltransferase; TIGRFAM: ATP/cobalamin adenosyltransferase; PFAM: cobalamin adenosyltransferase; Belongs to the Cob(I)alamin adenosyltransferase family. | PFAM: iron-containing alcohol dehydrogenase; KEGG: asu:Asuc_0591 bifunctional acetaldehyde-CoA/alcohol dehydrogenase; In the C-terminal section; belongs to the iron-containing alcohol dehydrogenase family. | 0.477 |
| Bsel_2172 | Bsel_2173 | Bsel_2172 | Bsel_2173 | KEGG: mei:Msip34_2147 ATP/cobalamin adenosyltransferase; TIGRFAM: ATP/cobalamin adenosyltransferase; PFAM: cobalamin adenosyltransferase; Belongs to the Cob(I)alamin adenosyltransferase family. | Molybdenum cofactor synthesis domain protein; May be involved in the biosynthesis of molybdopterin. Belongs to the MoaB/Mog family. | 0.546 |
| Bsel_2172 | Bsel_2245 | Bsel_2172 | Bsel_2245 | KEGG: mei:Msip34_2147 ATP/cobalamin adenosyltransferase; TIGRFAM: ATP/cobalamin adenosyltransferase; PFAM: cobalamin adenosyltransferase; Belongs to the Cob(I)alamin adenosyltransferase family. | methylmalonyl-CoA epimerase; KEGG: scl:sce1655 putative isobutyryl-CoA mutase, chain B; TIGRFAM: methylmalonyl-CoA epimerase; PFAM: cobalamin B12-binding domain protein; Glyoxalase/bleomycin resistance protein/dioxygenase. | 0.563 |