STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Bsel_2245methylmalonyl-CoA epimerase; KEGG: scl:sce1655 putative isobutyryl-CoA mutase, chain B; TIGRFAM: methylmalonyl-CoA epimerase; PFAM: cobalamin B12-binding domain protein; Glyoxalase/bleomycin resistance protein/dioxygenase. (281 aa)    
Predicted Functional Partners:
Bsel_2246
TIGRFAM: methylmalonyl-CoA mutase, large subunit; KEGG: gme:Gmet_3251 methylmalonyl-CoA mutase; PFAM: methylmalonyl-CoA mutase.
 0.999
icmF
methylmalonyl-CoA mutase, large subunit; Catalyzes the reversible interconversion of isobutyryl-CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly.
 
0.990
Bsel_2244
PFAM: carboxyl transferase; KEGG: mxa:MXAN_1113 propionyl-CoA carboxylase, beta subunit.
 
 
 0.984
Bsel_3187
KEGG: sfu:Sfum_0456 LAO/AO transport system ATPase; TIGRFAM: LAO/AO transport system ATPase; PFAM: ArgK protein.
  
 0.962
sucC
succinyl-CoA synthetase, beta subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.
  
 
 0.933
sucD
succinyl-CoA synthetase, alpha subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.
  
 
 0.931
Bsel_1353
TIGRFAM: 2-methylcitrate synthase/citrate synthase II; KEGG: bba:Bd0562 hypothetical protein; PFAM: Citrate synthase.
    
 0.875
Bsel_1816
PFAM: pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; Pyruvate/ketoisovalerate oxidoreductase; KEGG: dvm:DvMF_0184 pyruvate flavodoxin/ferredoxin oxidoreductase domain protein.
    
 0.875
Bsel_1899
PFAM: pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; KEGG: nam:NAMH_0242 pyruvate synthase subunit PorA.
    
 0.875
Bsel_2852
PFAM: pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; Pyruvate/ketoisovalerate oxidoreductase; KEGG: dde:Dde_1792 pyruvate ferredoxin oxidoreductase, alpha subunit.
    
 0.875
Your Current Organism:
Bacillus selenitireducens
NCBI taxonomy Id: 439292
Other names: Bacillus selenitireducens MLS10, [. selenitireducens MLS10, [Bacillus] selenitireducens MLS10
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.