STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Bsel_2702Transcriptional regulator, MerR family; KEGG: mxa:MXAN_5120 transcriptional activator TipA; PFAM: TipAS antibiotic-recognition domain protein; regulatory protein MerR; Transcription regulator MerR DNA binding; SMART: regulatory protein MerR. (254 aa)    
Predicted Functional Partners:
sigA
RNA polymerase, sigma 70 subunit, RpoD subfamily; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth.
 
 
 0.652
dnaJ
Chaperone protein DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, D [...]
  
 
 0.636
Bsel_2408
KEGG: tcx:Tcr_2014 chaperone DnaJ-like; PFAM: heat shock protein DnaJ domain protein; SMART: heat shock protein DnaJ domain protein.
  
 
 0.636
Bsel_1831
TIGRFAM: glutamine synthetase, type I; KEGG: dps:DP0930 glutamine synthetase; PFAM: glutamine synthetase catalytic region; glutamine synthetase beta-Grasp.
 
 
 0.631
rpoB
DNA-directed RNA polymerase, beta subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
    
 
 0.599
rpoA
DNA-directed RNA polymerase, alpha subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
  
 
 0.542
Bsel_2703
PFAM: short-chain dehydrogenase/reductase SDR; KR domain protein; KEGG: bxe:Bxe_C0635 putative short-chain dehydrogenase/reductase; Belongs to the short-chain dehydrogenases/reductases (SDR) family.
       0.530
rpoZ
DNA-directed RNA polymerase, omega subunit; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
   
 
 0.526
Bsel_2652
PFAM: protein of unknown function DUF214; KEGG: gem:GM21_2026 protein of unknown function DUF214.
 
     0.525
rpoC
DNA-directed RNA polymerase, beta' subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
    
 
 0.516
Your Current Organism:
Bacillus selenitireducens
NCBI taxonomy Id: 439292
Other names: Bacillus selenitireducens MLS10, [. selenitireducens MLS10, [Bacillus] selenitireducens MLS10
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.