| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| Bsel_0813 | Bsel_0991 | Bsel_0813 | Bsel_0991 | PFAM: 5'-Nucleotidase domain protein; metallophosphoesterase; S-layer domain protein; KEGG: mmw:Mmwyl1_4082 5'-nucleotidase domain-containing protein. | PFAM: 5'-Nucleotidase domain protein; metallophosphoesterase; S-layer domain protein; nucleic acid binding OB-fold tRNA/helicase-type; Endonuclease/exonuclease/phosphatase; KEGG: scl:sce0688 endonuclease/exonuclease/phosphatase family protein. | 0.933 |
| Bsel_0813 | Bsel_1067 | Bsel_0813 | Bsel_1067 | PFAM: 5'-Nucleotidase domain protein; metallophosphoesterase; S-layer domain protein; KEGG: mmw:Mmwyl1_4082 5'-nucleotidase domain-containing protein. | PFAM: 5'-Nucleotidase domain protein; metallophosphoesterase; S-layer domain protein; KEGG: sfu:Sfum_0741 5'-nucleotidase domain-containing protein; Belongs to the 5'-nucleotidase family. | 0.951 |
| Bsel_0813 | Bsel_1160 | Bsel_0813 | Bsel_1160 | PFAM: 5'-Nucleotidase domain protein; metallophosphoesterase; S-layer domain protein; KEGG: mmw:Mmwyl1_4082 5'-nucleotidase domain-containing protein. | PFAM: metallophosphoesterase; KEGG: seh:SeHA_C4439 5'-nucleotidase domain protein; Belongs to the 5'-nucleotidase family. | 0.944 |
| Bsel_0813 | Bsel_2067 | Bsel_0813 | Bsel_2067 | PFAM: 5'-Nucleotidase domain protein; metallophosphoesterase; S-layer domain protein; KEGG: mmw:Mmwyl1_4082 5'-nucleotidase domain-containing protein. | PFAM: deoxynucleoside kinase; KEGG: hypothetical protein. | 0.900 |
| Bsel_0813 | Bsel_2889 | Bsel_0813 | Bsel_2889 | PFAM: 5'-Nucleotidase domain protein; metallophosphoesterase; S-layer domain protein; KEGG: mmw:Mmwyl1_4082 5'-nucleotidase domain-containing protein. | PFAM: CMP/dCMP deaminase zinc-binding; KEGG: dds:Ddes_1618 CMP/dCMP deaminase zinc-binding. | 0.903 |
| Bsel_0813 | cmk | Bsel_0813 | Bsel_2148 | PFAM: 5'-Nucleotidase domain protein; metallophosphoesterase; S-layer domain protein; KEGG: mmw:Mmwyl1_4082 5'-nucleotidase domain-containing protein. | KEGG: pmu:PM0802 cytidylate kinase; TIGRFAM: cytidylate kinase; PFAM: cytidylate kinase region. | 0.900 |
| Bsel_0813 | tdk | Bsel_0813 | Bsel_3176 | PFAM: 5'-Nucleotidase domain protein; metallophosphoesterase; S-layer domain protein; KEGG: mmw:Mmwyl1_4082 5'-nucleotidase domain-containing protein. | KEGG: mxa:MXAN_5072 thymidine kinase; PFAM: thymidine kinase. | 0.903 |
| Bsel_0813 | thyA | Bsel_0813 | Bsel_1162 | PFAM: 5'-Nucleotidase domain protein; metallophosphoesterase; S-layer domain protein; KEGG: mmw:Mmwyl1_4082 5'-nucleotidase domain-containing protein. | Thymidylate synthase; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by- product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis. | 0.903 |
| Bsel_0813 | tmk | Bsel_0813 | Bsel_0034 | PFAM: 5'-Nucleotidase domain protein; metallophosphoesterase; S-layer domain protein; KEGG: mmw:Mmwyl1_4082 5'-nucleotidase domain-containing protein. | Thymidylate kinase; Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis; Belongs to the thymidylate kinase family. | 0.911 |
| Bsel_0991 | Bsel_0813 | Bsel_0991 | Bsel_0813 | PFAM: 5'-Nucleotidase domain protein; metallophosphoesterase; S-layer domain protein; nucleic acid binding OB-fold tRNA/helicase-type; Endonuclease/exonuclease/phosphatase; KEGG: scl:sce0688 endonuclease/exonuclease/phosphatase family protein. | PFAM: 5'-Nucleotidase domain protein; metallophosphoesterase; S-layer domain protein; KEGG: mmw:Mmwyl1_4082 5'-nucleotidase domain-containing protein. | 0.933 |
| Bsel_0991 | Bsel_1067 | Bsel_0991 | Bsel_1067 | PFAM: 5'-Nucleotidase domain protein; metallophosphoesterase; S-layer domain protein; nucleic acid binding OB-fold tRNA/helicase-type; Endonuclease/exonuclease/phosphatase; KEGG: scl:sce0688 endonuclease/exonuclease/phosphatase family protein. | PFAM: 5'-Nucleotidase domain protein; metallophosphoesterase; S-layer domain protein; KEGG: sfu:Sfum_0741 5'-nucleotidase domain-containing protein; Belongs to the 5'-nucleotidase family. | 0.932 |
| Bsel_0991 | Bsel_1160 | Bsel_0991 | Bsel_1160 | PFAM: 5'-Nucleotidase domain protein; metallophosphoesterase; S-layer domain protein; nucleic acid binding OB-fold tRNA/helicase-type; Endonuclease/exonuclease/phosphatase; KEGG: scl:sce0688 endonuclease/exonuclease/phosphatase family protein. | PFAM: metallophosphoesterase; KEGG: seh:SeHA_C4439 5'-nucleotidase domain protein; Belongs to the 5'-nucleotidase family. | 0.917 |
| Bsel_0991 | Bsel_2067 | Bsel_0991 | Bsel_2067 | PFAM: 5'-Nucleotidase domain protein; metallophosphoesterase; S-layer domain protein; nucleic acid binding OB-fold tRNA/helicase-type; Endonuclease/exonuclease/phosphatase; KEGG: scl:sce0688 endonuclease/exonuclease/phosphatase family protein. | PFAM: deoxynucleoside kinase; KEGG: hypothetical protein. | 0.900 |
| Bsel_0991 | Bsel_2889 | Bsel_0991 | Bsel_2889 | PFAM: 5'-Nucleotidase domain protein; metallophosphoesterase; S-layer domain protein; nucleic acid binding OB-fold tRNA/helicase-type; Endonuclease/exonuclease/phosphatase; KEGG: scl:sce0688 endonuclease/exonuclease/phosphatase family protein. | PFAM: CMP/dCMP deaminase zinc-binding; KEGG: dds:Ddes_1618 CMP/dCMP deaminase zinc-binding. | 0.904 |
| Bsel_0991 | cmk | Bsel_0991 | Bsel_2148 | PFAM: 5'-Nucleotidase domain protein; metallophosphoesterase; S-layer domain protein; nucleic acid binding OB-fold tRNA/helicase-type; Endonuclease/exonuclease/phosphatase; KEGG: scl:sce0688 endonuclease/exonuclease/phosphatase family protein. | KEGG: pmu:PM0802 cytidylate kinase; TIGRFAM: cytidylate kinase; PFAM: cytidylate kinase region. | 0.900 |
| Bsel_0991 | tdk | Bsel_0991 | Bsel_3176 | PFAM: 5'-Nucleotidase domain protein; metallophosphoesterase; S-layer domain protein; nucleic acid binding OB-fold tRNA/helicase-type; Endonuclease/exonuclease/phosphatase; KEGG: scl:sce0688 endonuclease/exonuclease/phosphatase family protein. | KEGG: mxa:MXAN_5072 thymidine kinase; PFAM: thymidine kinase. | 0.902 |
| Bsel_0991 | thyA | Bsel_0991 | Bsel_1162 | PFAM: 5'-Nucleotidase domain protein; metallophosphoesterase; S-layer domain protein; nucleic acid binding OB-fold tRNA/helicase-type; Endonuclease/exonuclease/phosphatase; KEGG: scl:sce0688 endonuclease/exonuclease/phosphatase family protein. | Thymidylate synthase; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by- product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis. | 0.903 |
| Bsel_0991 | tmk | Bsel_0991 | Bsel_0034 | PFAM: 5'-Nucleotidase domain protein; metallophosphoesterase; S-layer domain protein; nucleic acid binding OB-fold tRNA/helicase-type; Endonuclease/exonuclease/phosphatase; KEGG: scl:sce0688 endonuclease/exonuclease/phosphatase family protein. | Thymidylate kinase; Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis; Belongs to the thymidylate kinase family. | 0.921 |
| Bsel_1067 | Bsel_0813 | Bsel_1067 | Bsel_0813 | PFAM: 5'-Nucleotidase domain protein; metallophosphoesterase; S-layer domain protein; KEGG: sfu:Sfum_0741 5'-nucleotidase domain-containing protein; Belongs to the 5'-nucleotidase family. | PFAM: 5'-Nucleotidase domain protein; metallophosphoesterase; S-layer domain protein; KEGG: mmw:Mmwyl1_4082 5'-nucleotidase domain-containing protein. | 0.951 |
| Bsel_1067 | Bsel_0991 | Bsel_1067 | Bsel_0991 | PFAM: 5'-Nucleotidase domain protein; metallophosphoesterase; S-layer domain protein; KEGG: sfu:Sfum_0741 5'-nucleotidase domain-containing protein; Belongs to the 5'-nucleotidase family. | PFAM: 5'-Nucleotidase domain protein; metallophosphoesterase; S-layer domain protein; nucleic acid binding OB-fold tRNA/helicase-type; Endonuclease/exonuclease/phosphatase; KEGG: scl:sce0688 endonuclease/exonuclease/phosphatase family protein. | 0.932 |