STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Oant_1815PFAM: aminotransferase class I and II; KEGG: bme:BMEI0626 transcriptional regulator, GntR family. (410 aa)    
Predicted Functional Partners:
Oant_2388
Putative transcriptional regulator, GntR family; PFAM: regulatory protein GntR HTH; aminotransferase class I and II; KEGG: sme:SMc00490 putative transcription regulator protein.
  
     0.641
ilvC
Ketol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
       0.597
Oant_1814
Hypothetical protein.
       0.588
Oant_3461
Putative transcriptional regulator, GntR family; PFAM: regulatory protein GntR HTH; aminotransferase class I and II; KEGG: atc:AGR_L_244 hypothetical protein.
  
     0.570
Oant_1812
PFAM: regulatory protein TetR; KEGG: bmb:BruAb1_1377 transcriptional regulator, TetR family.
       0.464
Your Current Organism:
Ochrobactrum anthropi
NCBI taxonomy Id: 439375
Other names: O. anthropi ATCC 49188, Ochrobactrum anthropi ATCC 49188, Ochrobactrum anthropi DSM 6882, Ochrobactrum anthropi LMG 3331, Ochrobactrum anthropi str. ATCC 49188, Ochrobactrum anthropi strain ATCC 49188
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.