node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Oant_2040 | Oant_2041 | Oant_2040 | Oant_2041 | PFAM: protein of unknown function DUF1009; KEGG: bmb:BruAb1_1156 conserved hypothetical protein TIGR00148. | lipid-A-disaccharide synthase; Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. | 0.963 |
Oant_2040 | Oant_4269 | Oant_2040 | Oant_4269 | PFAM: protein of unknown function DUF1009; KEGG: bmb:BruAb1_1156 conserved hypothetical protein TIGR00148. | TIGRFAM: KpsF/GutQ family protein; PFAM: CBS domain containing protein; sugar isomerase (SIS); KEGG: bme:BMEII0021 polysialic acid capsule expression protein KpsF; Belongs to the SIS family. GutQ/KpsF subfamily. | 0.768 |
Oant_2040 | bamA | Oant_2040 | Oant_2036 | PFAM: protein of unknown function DUF1009; KEGG: bmb:BruAb1_1156 conserved hypothetical protein TIGR00148. | Surface antigen (D15); Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane. | 0.778 |
Oant_2040 | fabZ | Oant_2040 | Oant_2038 | PFAM: protein of unknown function DUF1009; KEGG: bmb:BruAb1_1156 conserved hypothetical protein TIGR00148. | Beta-hydroxyacyl-(acyl-carrier-protein) dehydratase FabZ; Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs. | 0.814 |
Oant_2040 | lpxA | Oant_2040 | Oant_2039 | PFAM: protein of unknown function DUF1009; KEGG: bmb:BruAb1_1156 conserved hypothetical protein TIGR00148. | acyl-(acyl-carrier-protein)--UDP-N- acetylglucosamine O-acyltransferase; Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. | 0.951 |
Oant_2040 | lpxC | Oant_2040 | Oant_1751 | PFAM: protein of unknown function DUF1009; KEGG: bmb:BruAb1_1156 conserved hypothetical protein TIGR00148. | UDP-3-0-acyl N-acetylglucosamine deacetylase; Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis; Belongs to the LpxC family. | 0.750 |
Oant_2040 | lpxD | Oant_2040 | Oant_2037 | PFAM: protein of unknown function DUF1009; KEGG: bmb:BruAb1_1156 conserved hypothetical protein TIGR00148. | UDP-3-O-(3-hydroxymyristoyl) glucosamine N-acyltransferase; Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3- hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. Belongs to the transferase hexapeptide repeat family. LpxD subfamily. | 0.944 |
Oant_2040 | lpxK | Oant_2040 | Oant_3047 | PFAM: protein of unknown function DUF1009; KEGG: bmb:BruAb1_1156 conserved hypothetical protein TIGR00148. | Tetraacyldisaccharide 4'-kinase; Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA). | 0.809 |
Oant_2041 | Oant_2040 | Oant_2041 | Oant_2040 | lipid-A-disaccharide synthase; Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. | PFAM: protein of unknown function DUF1009; KEGG: bmb:BruAb1_1156 conserved hypothetical protein TIGR00148. | 0.963 |
Oant_2041 | Oant_4269 | Oant_2041 | Oant_4269 | lipid-A-disaccharide synthase; Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. | TIGRFAM: KpsF/GutQ family protein; PFAM: CBS domain containing protein; sugar isomerase (SIS); KEGG: bme:BMEII0021 polysialic acid capsule expression protein KpsF; Belongs to the SIS family. GutQ/KpsF subfamily. | 0.892 |
Oant_2041 | bamA | Oant_2041 | Oant_2036 | lipid-A-disaccharide synthase; Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. | Surface antigen (D15); Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane. | 0.825 |
Oant_2041 | fabZ | Oant_2041 | Oant_2038 | lipid-A-disaccharide synthase; Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. | Beta-hydroxyacyl-(acyl-carrier-protein) dehydratase FabZ; Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs. | 0.906 |
Oant_2041 | lpxA | Oant_2041 | Oant_2039 | lipid-A-disaccharide synthase; Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. | acyl-(acyl-carrier-protein)--UDP-N- acetylglucosamine O-acyltransferase; Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. | 0.993 |
Oant_2041 | lpxC | Oant_2041 | Oant_1751 | lipid-A-disaccharide synthase; Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. | UDP-3-0-acyl N-acetylglucosamine deacetylase; Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis; Belongs to the LpxC family. | 0.855 |
Oant_2041 | lpxD | Oant_2041 | Oant_2037 | lipid-A-disaccharide synthase; Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. | UDP-3-O-(3-hydroxymyristoyl) glucosamine N-acyltransferase; Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3- hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. Belongs to the transferase hexapeptide repeat family. LpxD subfamily. | 0.996 |
Oant_2041 | lpxK | Oant_2041 | Oant_3047 | lipid-A-disaccharide synthase; Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. | Tetraacyldisaccharide 4'-kinase; Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA). | 0.984 |
Oant_4269 | Oant_2040 | Oant_4269 | Oant_2040 | TIGRFAM: KpsF/GutQ family protein; PFAM: CBS domain containing protein; sugar isomerase (SIS); KEGG: bme:BMEII0021 polysialic acid capsule expression protein KpsF; Belongs to the SIS family. GutQ/KpsF subfamily. | PFAM: protein of unknown function DUF1009; KEGG: bmb:BruAb1_1156 conserved hypothetical protein TIGR00148. | 0.768 |
Oant_4269 | Oant_2041 | Oant_4269 | Oant_2041 | TIGRFAM: KpsF/GutQ family protein; PFAM: CBS domain containing protein; sugar isomerase (SIS); KEGG: bme:BMEII0021 polysialic acid capsule expression protein KpsF; Belongs to the SIS family. GutQ/KpsF subfamily. | lipid-A-disaccharide synthase; Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. | 0.892 |
Oant_4269 | bamA | Oant_4269 | Oant_2036 | TIGRFAM: KpsF/GutQ family protein; PFAM: CBS domain containing protein; sugar isomerase (SIS); KEGG: bme:BMEII0021 polysialic acid capsule expression protein KpsF; Belongs to the SIS family. GutQ/KpsF subfamily. | Surface antigen (D15); Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane. | 0.593 |
Oant_4269 | lpxA | Oant_4269 | Oant_2039 | TIGRFAM: KpsF/GutQ family protein; PFAM: CBS domain containing protein; sugar isomerase (SIS); KEGG: bme:BMEII0021 polysialic acid capsule expression protein KpsF; Belongs to the SIS family. GutQ/KpsF subfamily. | acyl-(acyl-carrier-protein)--UDP-N- acetylglucosamine O-acyltransferase; Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. | 0.893 |