STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
Aboo_0010KEGG: tvo:TVN1212 hypothetical protein. (1503 aa)    
Predicted Functional Partners:
gyrB
DNA gyrase, B subunit; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
       0.574
Aboo_0478
KEGG: trq:TRQ2_0583 ABC transporter related; PFAM: ABC transporter related; SMART: AAA ATPase.
  
    0.511
Aboo_0586
Hypothetical protein; KEGG: msi:Msm_1203 zinc-dependent protease.
  
     0.511
Aboo_1484
KEGG: sto:ST0902 ABC transporter ATP-binding protein; PFAM: ABC transporter related; SMART: AAA ATPase.
  
    0.511
Aboo_0654
RecA-superfamily ATPase implicated in signal transduction-like protein; KEGG: ayw:AYWB_353 hypothetical protein.
  
     0.498
Your Current Organism:
Aciduliprofundum boonei
NCBI taxonomy Id: 439481
Other names: A. boonei T469, Aciduliprofundum boonei DSM 19572, Aciduliprofundum boonei T469, Aciduliprofundum boonei str. T469, Aciduliprofundum boonei strain T469
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.