STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
taw2Protein of unknown function Met10; S-adenosyl-L-methionine-dependent transferase that acts as a component of the wyosine derivatives biosynthesis pathway. Catalyzes the transfer of the alpha-amino-alpha-carboxypropyl (acp) group from S- adenosyl-L-methionine to 4-demethylwyosine (imG-14), forming 7- aminocarboxypropyl-demethylwyosine (wybutosine-86) at position 37 of tRNA(Phe). (346 aa)    
Predicted Functional Partners:
taw1
Wyosine base formation domain protein; Component of the wyosine derivatives biosynthesis pathway that catalyzes the condensation of N-methylguanine with 2 carbon atoms from pyruvate to form the tricyclic 4-demethylwyosine (imG-14) on guanosine-37 of tRNA(Phe).
 
  
 0.719
taw3
Protein of unknown function DUF207; S-adenosyl-L-methionine-dependent methyltransferase that acts as a component of the wyosine derivatives biosynthesis pathway. Probably methylates N-4 position of wybutosine-86 to produce wybutosine-72; Belongs to the TYW3 family.
 
  
 0.702
Aboo_0012
KEGG: mbu:Mbur_2059 hypothetical protein.
       0.693
Aboo_0013
PFAM: transglutaminase domain protein; KEGG: ckr:CKR_2935 hypothetical protein.
       0.693
Aboo_0756
TIGRFAM: MiaB-like tRNA modifying enzyme; RNA modification enzyme, MiaB family; PFAM: Radical SAM domain protein; Protein of unknown function UPF0004; KEGG: pho:PH1875 hypothetical protein; SMART: Elongator protein 3/MiaB/NifB.
  
  
 0.526
pus10
THUMP domain protein; Responsible for synthesis of pseudouridine from uracil-54 and uracil-55 in the psi GC loop of transfer RNAs.
  
  
 0.518
rpl21e
PFAM: Ribosomal protein L21e; KEGG: mka:MK1660 50S ribosomal protein L21e; Belongs to the eukaryotic ribosomal protein eL21 family.
  
     0.503
Aboo_0797
PFAM: nucleic acid binding OB-fold tRNA/helicase-type; KEGG: pto:PTO0673 single-stranded DNA-binding protein.
  
    0.485
Aboo_0725
Aspartate/glutamate/uridylate kinase; Catalyzes the formation of isopentenyl diphosphate (IPP), the building block of all isoprenoids.
  
     0.441
Your Current Organism:
Aciduliprofundum boonei
NCBI taxonomy Id: 439481
Other names: A. boonei T469, Aciduliprofundum boonei DSM 19572, Aciduliprofundum boonei T469, Aciduliprofundum boonei str. T469, Aciduliprofundum boonei strain T469
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