STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
psmBProteasome endopeptidase complex, beta subunit; Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation. (210 aa)    
Predicted Functional Partners:
Aboo_0723
PFAM: 20S proteasome A and B subunits; Proteasome alpha-subunit; KEGG: mae:Maeo_0181 proteasome subunit alpha.
 
 
 0.919
pan
26S proteasome subunit P45 family; ATPase which is responsible for recognizing, binding, unfolding and translocation of substrate proteins into the archaeal 20S proteasome core particle. Is essential for opening the gate of the 20S proteasome via an interaction with its C-terminus, thereby allowing substrate entry and access to the site of proteolysis. Thus, the C- termini of the proteasomal ATPase function like a 'key in a lock' to induce gate opening and therefore regulate proteolysis. Unfolding activity requires energy from ATP hydrolysis, whereas ATP binding alone promotes ATPase-2 [...]
  
 0.914
psmA
Proteasome endopeptidase complex, alpha subunit; Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation.
 
 
0.864
Aboo_0122
TIGRFAM: KH-domain/beta-lactamase-domain protein; PFAM: RNA-metabolising metallo-beta-lactamase; KEGG: tvo:TVN0664 metal-dependent RNase; SMART: beta-lactamase domain protein; KH domain protein.
     
 0.840
Aboo_0077
KEGG: tac:Ta0623 hypothetical protein.
   
 0.776
glpK
Glycerol kinase; Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate.
   
 0.774
Aboo_1312
PFAM: Ribosomal protein L40e; KEGG: mka:MK0641 50S ribosomal protein L40e.
   
 0.695
Aboo_0314
PFAM: peptidase M50; KEGG: tac:Ta1274 sterol-regulatory element-binding proteins intramembrane protease related protein.
 
 
 0.602
Aboo_0124
PFAM: ABC-3 protein; KEGG: afu:AF1981 ABC transporter, permease protein.
       0.588
Aboo_0125
KEGG: tsi:TSIB_0411 ABC transporter ATP-binding protein; PFAM: ABC transporter related; SMART: AAA ATPase.
       0.588
Your Current Organism:
Aciduliprofundum boonei
NCBI taxonomy Id: 439481
Other names: A. boonei T469, Aciduliprofundum boonei DSM 19572, Aciduliprofundum boonei T469, Aciduliprofundum boonei str. T469, Aciduliprofundum boonei strain T469
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.